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Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity.
Vanderbeke L, Van Mol P, Van Herck Y, De Smet F, Humblet-Baron S, Martinod K, Antoranz A, Arijs I, Boeckx B, Bosisio FM, Casaer M, Dauwe D, De Wever W, Dooms C, Dreesen E, Emmaneel A, Filtjens J, Gouwy M, Gunst J, Hermans G, Jansen S, Lagrou K, Liston A, Lorent N, Meersseman P, Mercier T, Neyts J, Odent J, Panovska D, Penttila PA, Pollet E, Proost P, Qian J, Quintelier K, Raes J, Rex S, Saeys Y, Sprooten J, Tejpar S, Testelmans D, Thevissen K, Van Buyten T, Vandenhaute J, Van Gassen S, Velásquez Pereira LC, Vos R, Weynand B, Wilmer A, Yserbyt J, Garg AD, Matthys P, Wouters C, Lambrechts D, Wauters E, Wauters J. Vanderbeke L, et al. Among authors: saeys y. Nat Commun. 2021 Jul 5;12(1):4117. doi: 10.1038/s41467-021-24360-w. Nat Commun. 2021. PMID: 34226537 Free PMC article.
Meta-analysis of (single-cell method) benchmarks reveals the need for extensibility and interoperability.
Sonrel A, Luetge A, Soneson C, Mallona I, Germain PL, Knyazev S, Gilis J, Gerber R, Seurinck R, Paul D, Sonder E, Crowell HL, Fanaswala I, Al-Ajami A, Heidari E, Schmeing S, Milosavljevic S, Saeys Y, Mangul S, Robinson MD. Sonrel A, et al. Among authors: saeys y. Genome Biol. 2023 May 17;24(1):119. doi: 10.1186/s13059-023-02962-5. Genome Biol. 2023. PMID: 37198712 Free PMC article.
Myeloid cell heterogeneity in cancer: not a single cell alike.
Kiss M, Van Gassen S, Movahedi K, Saeys Y, Laoui D. Kiss M, et al. Among authors: saeys y. Cell Immunol. 2018 Aug;330:188-201. doi: 10.1016/j.cellimm.2018.02.008. Epub 2018 Feb 14. Cell Immunol. 2018. PMID: 29482836 Review.
Mechanical strain determines the site-specific localization of inflammation and tissue damage in arthritis.
Cambré I, Gaublomme D, Burssens A, Jacques P, Schryvers N, De Muynck A, Meuris L, Lambrecht S, Carter S, de Bleser P, Saeys Y, Van Hoorebeke L, Kollias G, Mack M, Simoens P, Lories R, Callewaert N, Schett G, Elewaut D. Cambré I, et al. Among authors: saeys y. Nat Commun. 2018 Nov 5;9(1):4613. doi: 10.1038/s41467-018-06933-4. Nat Commun. 2018. PMID: 30397205 Free PMC article.
171 results