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Page 1
Concurrent loss of LKB1 and KEAP1 enhances SHMT-mediated antioxidant defence in KRAS-mutant lung cancer.
Lee HM, Muhammad N, Lieu EL, Cai F, Mu J, Ha YS, Cao G, Suchors C, Joves K, Chronis C, Li K, Ducker GS, Olszewski K, Cai L, Allison DB, Bachert SE, Ewing WR, Wong H, Seo H, Kim IY, Faubert B, Kim J, Kim J. Lee HM, et al. Among authors: lieu el. Nat Metab. 2024 Jul;6(7):1310-1328. doi: 10.1038/s42255-024-01066-z. Epub 2024 Jun 14. Nat Metab. 2024. PMID: 38877143
The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1 mutant lung cancer.
Kim J, Lee HM, Cai F, Ko B, Yang C, Lieu EL, Muhammad N, Rhyne S, Li K, Haloul M, Gu W, Faubert B, Kaushik AK, Cai L, Kasiri S, Marriam U, Nham K, Girard L, Wang H, Sun X, Kim J, Minna JD, Unsal-Kacmaz K, DeBerardinis RJ. Kim J, et al. Among authors: lieu el. Nat Metab. 2020 Dec;2(12):1401-1412. doi: 10.1038/s42255-020-00316-0. Epub 2020 Nov 30. Nat Metab. 2020. PMID: 33257855 Free PMC article.
Amino acids in cancer.
Lieu EL, Nguyen T, Rhyne S, Kim J. Lieu EL, et al. Exp Mol Med. 2020 Jan;52(1):15-30. doi: 10.1038/s12276-020-0375-3. Epub 2020 Jan 24. Exp Mol Med. 2020. PMID: 31980738 Free PMC article. Review.