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Page 1
A Fusion Protein Complex that Combines IL-12, IL-15, and IL-18 Signaling to Induce Memory-Like NK Cells for Cancer Immunotherapy.
Becker-Hapak MK, Shrestha N, McClain E, Dee MJ, Chaturvedi P, Leclerc GM, Marsala LI, Foster M, Schappe T, Tran J, Desai S, Neal CC, Pence P, Wong P, Wagner JA, Russler-Germain DA, Zhu X, Spanoudis CM, Gallo VL, Echeverri CA, Ramirez LL, You L, Egan JO, Rhode PR, Jiao JA, Muniz GJ, Jeng EK, Prendes CA, Sullivan RP, Berrien-Elliott MM, Wong HC, Fehniger TA. Becker-Hapak MK, et al. Among authors: shrestha n. Cancer Immunol Res. 2021 Sep;9(9):1071-1087. doi: 10.1158/2326-6066.CIR-20-1002. Epub 2021 Jul 9. Cancer Immunol Res. 2021. PMID: 34244297 Free PMC article.
Immunotherapeutic HCW9218 augments anti-tumor activity of chemotherapy via NK cell-mediated reduction of therapy-induced senescent cells.
Chaturvedi P, George V, Shrestha N, Wang M, Dee MJ, Zhu X, Liu B, Egan J, D'Eramo F, Spanoudis C, Gallo V, Echeverri C, You L, Kong L, Fang B, Jeng EK, Rhode PR, Wong HC. Chaturvedi P, et al. Among authors: shrestha n. Mol Ther. 2022 Mar 2;30(3):1171-1187. doi: 10.1016/j.ymthe.2022.01.025. Epub 2022 Jan 17. Mol Ther. 2022. PMID: 35051615 Free PMC article.
A novel interleukin-2-based fusion molecule, HCW9302, differentially promotes regulatory T cell expansion to treat atherosclerosis in mice.
Zhu X, Li Q, George V, Spanoudis C, Gilkes C, Shrestha N, Liu B, Kong L, You L, Echeverri C, Li L, Wang Z, Chaturvedi P, Muniz GJ, Egan JO, Rhode PR, Wong HC. Zhu X, et al. Among authors: shrestha n. Front Immunol. 2023 Jan 25;14:1114802. doi: 10.3389/fimmu.2023.1114802. eCollection 2023. Front Immunol. 2023. PMID: 36761778 Free PMC article.
Immunotherapeutic approach to reduce senescent cells and alleviate senescence-associated secretory phenotype in mice.
Shrestha N, Chaturvedi P, Zhu X, Dee MJ, George V, Janney C, Egan JO, Liu B, Foster M, Marsala L, Wong P, Cubitt CC, Foltz JA, Tran J, Schappe T, Hsiao K, Leclerc GM, You L, Echeverri C, Spanoudis C, Carvalho A, Kanakaraj L, Gilkes C, Encalada N, Kong L, Wang M, Fang B, Wang Z, Jiao JA, Muniz GJ, Jeng EK, Valdivieso N, Li L, Deth R, Berrien-Elliott MM, Fehniger TA, Rhode PR, Wong HC. Shrestha N, et al. Aging Cell. 2023 May;22(5):e13806. doi: 10.1111/acel.13806. Epub 2023 Mar 26. Aging Cell. 2023. PMID: 36967480 Free PMC article.
A "Prime and Expand" strategy using the multifunctional fusion proteins to generate memory-like NK cells for cell therapy.
Shrestha N, Dee MJ, Chaturvedi P, Leclerc GM, Mathyer M, Dufour C, Arthur L, Becker-Hapak M, Foster M, McClain E, Pena NV, Kage K, Zhu X, George V, Liu B, Egan J, Echeverri C, Wang M, You L, Kong L, Li L, Berrien-Elliott MM, Cooper ML, Fehniger TA, Rhode PR, Wong HC. Shrestha N, et al. Cancer Immunol Immunother. 2024 Jul 3;73(9):179. doi: 10.1007/s00262-024-03765-8. Cancer Immunol Immunother. 2024. PMID: 38960949 Free PMC article.
Parental motivations and perceived barriers to participating in pediatric vaccine clinical trials: Findings from the OCV-S trial in Nepal.
Chapagain RH, Adhikari S, Kunwar K, Thapa P, Maharjan J, Giri BR, Shrestha NJ, Shrestha AK, Shrestha SK, Tamang SM, Kim DR, Saluja T, Wartel A, Lynch J, Song KR. Chapagain RH, et al. Among authors: shrestha nj. Vaccine X. 2024 Nov 22;21:100585. doi: 10.1016/j.jvacx.2024.100585. eCollection 2024 Dec. Vaccine X. 2024. PMID: 39686923 Free PMC article.
Socio-economic factors associated with cancer stigma among apparently healthy women in two selected municipalities Nepal.
Paneru B, Karmacharya A, Makaju S, Kafle D, Poudel L, Mali S, Timsina P, Shrestha N, Timalsena D, Chaudhary K, Bhandari N, Rai P, Shakya S, Spiegelman D, Sheth SS, Stangl A, Eastment MC, Shrestha A. Paneru B, et al. Among authors: shrestha n. PLoS One. 2024 Dec 16;19(12):e0301059. doi: 10.1371/journal.pone.0301059. eCollection 2024. PLoS One. 2024. PMID: 39680514 Free PMC article.
A rare case report of penile myiasis in a catheterized patient.
Ghimire S, Adhikari P, Shrestha N, Luitel B, Chalise PR, Mandal S. Ghimire S, et al. Among authors: shrestha n. Int J Surg Case Rep. 2024 Dec 13;126:110744. doi: 10.1016/j.ijscr.2024.110744. Online ahead of print. Int J Surg Case Rep. 2024. PMID: 39675063 Free PMC article.
Socioeconomic, Behavioural, and Health-related Characteristics of Older Adults.
Suvedi BK, Karmacharya I, Karkee SB, Myia SD, Ghimire S, Karki K, Singh DR, Paudel S, Marasine NR, Pandey S, Adhikari R, Kafle B, Shrestha N. Suvedi BK, et al. Among authors: shrestha n. J Nepal Health Res Counc. 2024 Oct 3;22(2):419-429. doi: 10.33314/jnhrc.v22i02.5392. J Nepal Health Res Counc. 2024. PMID: 39572966
830 results