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1,2-Difunctionalized bicyclo[1.1.1]pentanes: Long-sought-after mimetics for ortho/meta-substituted arenes.
Zhao JX, Chang YX, He C, Burke BJ, Collins MR, Del Bel M, Elleraas J, Gallego GM, Montgomery TP, Mousseau JJ, Nair SK, Perry MA, Spangler JE, Vantourout JC, Baran PS. Zhao JX, et al. Among authors: mousseau jj. Proc Natl Acad Sci U S A. 2021 Jul 13;118(28):e2108881118. doi: 10.1073/pnas.2108881118. Proc Natl Acad Sci U S A. 2021. PMID: 34244445 Free PMC article.
Strain-Release Heteroatom Functionalization: Development, Scope, and Stereospecificity.
Lopchuk JM, Fjelbye K, Kawamata Y, Malins LR, Pan CM, Gianatassio R, Wang J, Prieto L, Bradow J, Brandt TA, Collins MR, Elleraas J, Ewanicki J, Farrell W, Fadeyi OO, Gallego GM, Mousseau JJ, Oliver R, Sach NW, Smith JK, Spangler JE, Zhu H, Zhu J, Baran PS. Lopchuk JM, et al. Among authors: mousseau jj. J Am Chem Soc. 2017 Mar 1;139(8):3209-3226. doi: 10.1021/jacs.6b13229. Epub 2017 Feb 20. J Am Chem Soc. 2017. PMID: 28140573 Free PMC article.
A General Amino Acid Synthesis Enabled by Innate Radical Cross-Coupling.
Ni S, Garrido-Castro AF, Merchant RR, de Gruyter JN, Schmitt DC, Mousseau JJ, Gallego GM, Yang S, Collins MR, Qiao JX, Yeung KS, Langley DR, Poss MA, Scola PM, Qin T, Baran PS. Ni S, et al. Among authors: mousseau jj. Angew Chem Int Ed Engl. 2018 Oct 26;57(44):14560-14565. doi: 10.1002/anie.201809310. Epub 2018 Oct 15. Angew Chem Int Ed Engl. 2018. PMID: 30212610 Free PMC article.
A Radical Approach to Anionic Chemistry: Synthesis of Ketones, Alcohols, and Amines.
Ni S, Padial NM, Kingston C, Vantourout JC, Schmitt DC, Edwards JT, Kruszyk MM, Merchant RR, Mykhailiuk PK, Sanchez BB, Yang S, Perry MA, Gallego GM, Mousseau JJ, Collins MR, Cherney RJ, Lebed PS, Chen JS, Qin T, Baran PS. Ni S, et al. Among authors: mousseau jj. J Am Chem Soc. 2019 Apr 24;141(16):6726-6739. doi: 10.1021/jacs.9b02238. Epub 2019 Apr 16. J Am Chem Soc. 2019. PMID: 30943023 Free PMC article.
Early Clinical Development of Lufotrelvir as a Potential Therapy for COVID-19.
Allais C, Bernhardson D, Brown AR, Chinigo GM, Desrosiers JN, DiRico KJ, Hotham I, Jones BP, Kulkarni SA, Lewis CA, Lira R, Loach RP, Morse PD, Mousseau JJ, Perry MA, Peng Z, Place DW, Rane AM, Samp L, Singer RA, Wang Z, Weisenburger GA, Yayla HG, Zanghi JM. Allais C, et al. Among authors: mousseau jj. Org Process Res Dev. 2023 Feb 3:acs.oprd.2c00375. doi: 10.1021/acs.oprd.2c00375. Online ahead of print. Org Process Res Dev. 2023. PMID: 37552749 Review.
Synthesis of Enantioenriched α-Chiral Bicyclo[1.1.1]pentanes.
Wong MLJ, Mousseau JJ, Mansfield SJ, Anderson EA. Wong MLJ, et al. Among authors: mousseau jj. Org Lett. 2019 Apr 5;21(7):2408-2411. doi: 10.1021/acs.orglett.9b00691. Epub 2019 Mar 14. Org Lett. 2019. PMID: 30869907
74 results