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Thousands of induced germline mutations affecting immune cells identified by automated meiotic mapping coupled with machine learning.
Xu D, Lyon S, Bu CH, Hildebrand S, Choi JH, Zhong X, Liu A, Turer EE, Zhang Z, Russell J, Ludwig S, Mahrt E, Nair-Gill E, Shi H, Wang Y, Zhang D, Yue T, Wang KW, SoRelle JA, Su L, Misawa T, McAlpine W, Sun L, Wang J, Zhan X, Choi M, Farokhnia R, Sakla A, Schneider S, Coco H, Coolbaugh G, Hayse B, Mazal S, Medler D, Nguyen B, Rodriguez E, Wadley A, Tang M, Li X, Anderton P, Keller K, Press A, Scott L, Quan J, Cooper S, Collie T, Qin B, Cardin J, Simpson R, Tadesse M, Sun Q, Wise CA, Rios JJ, Moresco EMY, Beutler B. Xu D, et al. Among authors: keller k. Proc Natl Acad Sci U S A. 2021 Jul 13;118(28):e2106786118. doi: 10.1073/pnas.2106786118. Proc Natl Acad Sci U S A. 2021. PMID: 34260399 Free PMC article.
Essential requirement for IER3IP1 in B cell development.
Zhong X, Moresco JJ, Keller K, Lazaro DR, Ely C, Moresco EMY, Beutler B, Choi JH. Zhong X, et al. Among authors: keller k. Proc Natl Acad Sci U S A. 2023 Nov 14;120(46):e2312810120. doi: 10.1073/pnas.2312810120. Epub 2023 Nov 7. Proc Natl Acad Sci U S A. 2023. PMID: 37934820 Free PMC article.
OVOL2 sustains postnatal thymic epithelial cell identity.
Zhong X, Peddada N, Wang J, Moresco JJ, Zhan X, Shelton JM, SoRelle JA, Keller K, Lazaro DR, Moresco EMY, Choi JH, Beutler B. Zhong X, et al. Among authors: keller k. Nat Commun. 2023 Nov 27;14(1):7786. doi: 10.1038/s41467-023-43456-z. Nat Commun. 2023. PMID: 38012144 Free PMC article.
Essential role of MFSD1-GLMP-GIMAP5 in lymphocyte survival and liver homeostasis.
Zhong X, Moresco JJ, Diedrich JK, Pinto AM, SoRelle JA, Wang J, Keller K, Ludwig S, Moresco EMY, Beutler B, Choi JH. Zhong X, et al. Among authors: keller k. Proc Natl Acad Sci U S A. 2023 Dec 12;120(50):e2314429120. doi: 10.1073/pnas.2314429120. Epub 2023 Dec 6. Proc Natl Acad Sci U S A. 2023. PMID: 38055739 Free PMC article.
1,340 results