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cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila.
Slavik KM, Morehouse BR, Ragucci AE, Zhou W, Ai X, Chen Y, Li L, Wei Z, Bähre H, König M, Seifert R, Lee ASY, Cai H, Imler JL, Kranzusch PJ. Slavik KM, et al. Among authors: cai h. Nature. 2021 Sep;597(7874):109-113. doi: 10.1038/s41586-021-03743-5. Epub 2021 Jul 14. Nature. 2021. PMID: 34261127 Free PMC article.
The Kinase IKKβ Regulates a STING- and NF-κB-Dependent Antiviral Response Pathway in Drosophila.
Goto A, Okado K, Martins N, Cai H, Barbier V, Lamiable O, Troxler L, Santiago E, Kuhn L, Paik D, Silverman N, Holleufer A, Hartmann R, Liu J, Peng T, Hoffmann JA, Meignin C, Daeffler L, Imler JL. Goto A, et al. Among authors: cai h. Immunity. 2018 Aug 21;49(2):225-234.e4. doi: 10.1016/j.immuni.2018.07.013. Epub 2018 Aug 14. Immunity. 2018. PMID: 30119996 Free PMC article.
Two cGAS-like receptors induce antiviral immunity in Drosophila.
Holleufer A, Winther KG, Gad HH, Ai X, Chen Y, Li L, Wei Z, Deng H, Liu J, Frederiksen NA, Simonsen B, Andersen LL, Kleigrewe K, Dalskov L, Pichlmair A, Cai H, Imler JL, Hartmann R. Holleufer A, et al. Among authors: cai h. Nature. 2021 Sep;597(7874):114-118. doi: 10.1038/s41586-021-03800-z. Epub 2021 Jul 14. Nature. 2021. PMID: 34261128
A novel virus-induced cyclic dinucleotide, 2'3'-c-di-GMP, mediates STING-dependent antiviral immunity in Drosophila.
Cai H, Li L, Slavik K, Huang J, Yin T, Hédelin L, Xiang Z, Yang Y, Li X, Chen Y, Wei Z, Deng H, Chen D, Jiao R, Martins N, Meignin C, Kranzusch P, Imler JL. Cai H, et al. bioRxiv [Preprint]. 2023 May 9:2023.05.08.539652. doi: 10.1101/2023.05.08.539652. bioRxiv. 2023. Update in: Immunity. 2023 Sep 12;56(9):1991-2005.e9. doi: 10.1016/j.immuni.2023.08.006 PMID: 37214844 Free PMC article. Updated. Preprint.
Evolutionary immunology to explore original antiviral strategies.
Imler JL, Cai H, Meignin C, Martins N. Imler JL, et al. Among authors: cai h. Philos Trans R Soc Lond B Biol Sci. 2024 May 6;379(1901):20230068. doi: 10.1098/rstb.2023.0068. Epub 2024 Mar 18. Philos Trans R Soc Lond B Biol Sci. 2024. PMID: 38497262 Review.
8,943 results