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Adenovirus vector vaccination reprograms pulmonary fibroblastic niches to support protective inflating memory CD8+ T cells.
Cupovic J, Ring SS, Onder L, Colston JM, Lütge M, Cheng HW, De Martin A, Provine NM, Flatz L, Oxenius A, Scandella E, Krebs P, Engeler D, Klenerman P, Ludewig B. Cupovic J, et al. Among authors: flatz l. Nat Immunol. 2021 Aug;22(8):1042-1051. doi: 10.1038/s41590-021-00969-3. Epub 2021 Jul 15. Nat Immunol. 2021. PMID: 34267375 Free PMC article.
Neuropathological assessment of the olfactory bulb and tract in individuals with COVID-19.
Lengacher NA, Tomlinson JJ, Jochum AK, Franz J, Hasan Ali O, Flatz L, Jochum W, Penninger J; aSCENT-PD Investigators; Stadelmann C, Woulfe JM, Schlossmacher MG. Lengacher NA, et al. Among authors: flatz l. Acta Neuropathol Commun. 2024 May 3;12(1):70. doi: 10.1186/s40478-024-01761-8. Acta Neuropathol Commun. 2024. PMID: 38698465 Free PMC article.
Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity.
Flatz L, Hegazy AN, Bergthaler A, Verschoor A, Claus C, Fernandez M, Gattinoni L, Johnson S, Kreppel F, Kochanek S, Broek Mv, Radbruch A, Lévy F, Lambert PH, Siegrist CA, Restifo NP, Löhning M, Ochsenbein AF, Nabel GJ, Pinschewer DD. Flatz L, et al. Nat Med. 2010 Mar;16(3):339-45. doi: 10.1038/nm.2104. Epub 2010 Feb 7. Nat Med. 2010. PMID: 20139992 Free PMC article.
Transcriptional profiles reveal a stepwise developmental program of memory CD8(+) T cell differentiation.
Roychoudhuri R, Lefebvre F, Honda M, Pan L, Ji Y, Klebanoff CA, Nichols CN, Fourati S, Hegazy AN, Goulet JP, Gattinoni L, Nabel GJ, Gilliet M, Cameron M, Restifo NP, Sékaly RP, Flatz L. Roychoudhuri R, et al. Among authors: flatz l. Vaccine. 2015 Feb 11;33(7):914-23. doi: 10.1016/j.vaccine.2014.10.007. Epub 2014 Nov 1. Vaccine. 2015. PMID: 25446821 Free PMC article.
Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage.
Bhattacharya A, Hegazy AN, Deigendesch N, Kosack L, Cupovic J, Kandasamy RK, Hildebrandt A, Merkler D, Kühl AA, Vilagos B, Schliehe C, Panse I, Khamina K, Baazim H, Arnold I, Flatz L, Xu HC, Lang PA, Aderem A, Takaoka A, Superti-Furga G, Colinge J, Ludewig B, Löhning M, Bergthaler A. Bhattacharya A, et al. Among authors: flatz l. Immunity. 2015 Nov 17;43(5):974-86. doi: 10.1016/j.immuni.2015.10.013. Immunity. 2015. PMID: 26588782 Free PMC article.
Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression.
Kalkavan H, Sharma P, Kasper S, Helfrich I, Pandyra AA, Gassa A, Virchow I, Flatz L, Brandenburg T, Namineni S, Heikenwalder M, Höchst B, Knolle PA, Wollmann G, von Laer D, Drexler I, Rathbun J, Cannon PM, Scheu S, Bauer J, Chauhan J, Häussinger D, Willimsky G, Löhning M, Schadendorf D, Brandau S, Schuler M, Lang PA, Lang KS. Kalkavan H, et al. Among authors: flatz l. Nat Commun. 2017 Mar 1;8:14447. doi: 10.1038/ncomms14447. Nat Commun. 2017. PMID: 28248314 Free PMC article.
132 results