Cunningham KP - Search Results

1

The Prostacyclin Analogue, Treprostinil, Used in the Treatment of Pulmonary Arterial Hypertension, is a Potent Antagonist of TREK-1 and TREK-2 Potassium Channels.

Cunningham KP, Clapp LH, Mathie A, Veale EL. Cunningham KP, et al. Front Pharmacol. 2021 Jun 29;12:705421. doi: 10.3389/fphar.2021.705421. eCollection 2021. Front Pharmacol. 2021. PMID: 34267666 Free PMC article.

2

Characterization and regulation of wild-type and mutant TASK-1 two pore domain potassium channels indicated in pulmonary arterial hypertension.

Cunningham KP, Holden RG, Escribano-Subias PM, Cogolludo A, Veale EL, Mathie A. Cunningham KP, et al. J Physiol. 2019 Feb;597(4):1087-1101. doi: 10.1113/JP277275. Epub 2018 Nov 24. J Physiol. 2019. PMID: 30365877 Free PMC article.

3

Effects of the ventilatory stimulant, doxapram on human TASK-3 (KCNK9, K2P9.1) channels and TASK-1 (KCNK3, K2P3.1) channels.

Cunningham KP, MacIntyre DE, Mathie A, Veale EL. Cunningham KP, et al. Acta Physiol (Oxf). 2020 Feb;228(2):e13361. doi: 10.1111/apha.13361. Epub 2019 Sep 18. Acta Physiol (Oxf). 2020. PMID: 31423744 Free PMC article.

4

Two-Pore Domain Potassium Channels as Drug Targets: Anesthesia and Beyond.

Mathie A, Veale EL, Cunningham KP, Holden RG, Wright PD. Mathie A, et al. Among authors: cunningham kp. Annu Rev Pharmacol Toxicol. 2021 Jan 6;61:401-420. doi: 10.1146/annurev-pharmtox-030920-111536. Epub 2020 Jul 17. Annu Rev Pharmacol Toxicol. 2021. PMID: 32679007

5

Artemisinin inhibits neutrophil and macrophage chemotaxis, cytokine production and NET release.

Morad HOJ, Luqman S, Pinto LG, Cunningham KP, Vilar B, Clayton G, Shankar-Hari M, McNaughton PA. Morad HOJ, et al. Among authors: cunningham kp. Sci Rep. 2022 Jun 30;12(1):11078. doi: 10.1038/s41598-022-15214-6. Sci Rep. 2022. PMID: 35773325 Free PMC article.

6

PUFA stabilizes a conductive state of the selectivity filter in IKs channels.

Golluscio A, Eldstrom J, Jowais JJ, Perez ME, Cunningham KP, De La Cruz A, Wu X, Corradi V, Tieleman DP, Fedida D, Larsson HP. Golluscio A, et al. Among authors: cunningham kp. Elife. 2024 Oct 31;13:RP95852. doi: 10.7554/eLife.95852. Elife. 2024. PMID: 39480699 Free PMC article.

7

Propofol rescues voltage-dependent gating of HCN1 channel epilepsy mutants.

Kim ED, Wu X, Lee S, Tibbs GR, Cunningham KP, Di Zanni E, Perez ME, Goldstein PA, Accardi A, Larsson HP, Nimigean CM. Kim ED, et al. Among authors: cunningham kp. Nature. 2024 Aug;632(8024):451-459. doi: 10.1038/s41586-024-07743-z. Epub 2024 Jul 31. Nature. 2024. PMID: 39085604

8

Loose Coupling between the Voltage Sensor and the Activation Gate in Mammalian HCN Channels Suggests a Gating Mechanism.

Wu X, Cunningham KP, Bruening-Wright A, Pandey S, Larsson HP. Wu X, et al. Among authors: cunningham kp. Int J Mol Sci. 2024 Apr 13;25(8):4309. doi: 10.3390/ijms25084309. Int J Mol Sci. 2024. PMID: 38673895 Free PMC article.

9

Similar voltage-sensor movement in spHCN channels can cause closing, opening, or inactivation.

Wu X, Cunningham KP, Ramentol R, Perez ME, Larsson HP. Wu X, et al. Among authors: cunningham kp. J Gen Physiol. 2023 May 1;155(5):e202213170. doi: 10.1085/jgp.202213170. Epub 2023 Feb 8. J Gen Physiol. 2023. PMID: 36752823 Free PMC article.

10

Variability of the diameter and taper of size #30, 0.04 nickel-titanium rotary files.

Lask JT, Walker MP, Kulild JC, Cunningham KP, Shull PA. Lask JT, et al. Among authors: cunningham kp. J Endod. 2006 Dec;32(12):1171-3. doi: 10.1016/j.joen.2006.07.013. Epub 2006 Oct 19. J Endod. 2006. PMID: 17174675

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