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Page 1
Extracellular detection of neuronal coupling.
Guzman E, Cheng Z, Hansma PK, Tovar KR, Petzold LR, Kosik KS. Guzman E, et al. Sci Rep. 2021 Jul 19;11(1):14733. doi: 10.1038/s41598-021-94282-6. Sci Rep. 2021. PMID: 34282275 Free PMC article.
Functional neuronal circuitry and oscillatory dynamics in human brain organoids.
Sharf T, van der Molen T, Glasauer SMK, Guzman E, Buccino AP, Luna G, Cheng Z, Audouard M, Ranasinghe KG, Kudo K, Nagarajan SS, Tovar KR, Petzold LR, Hierlemann A, Hansma PK, Kosik KS. Sharf T, et al. Among authors: guzman e. Nat Commun. 2022 Jul 29;13(1):4403. doi: 10.1038/s41467-022-32115-4. Nat Commun. 2022. PMID: 35906223 Free PMC article.
Human tau mutations in cerebral organoids induce a progressive dyshomeostasis of cholesterol.
Glasauer SMK, Goderie SK, Rauch JN, Guzman E, Audouard M, Bertucci T, Joy S, Rommelfanger E, Luna G, Keane-Rivera E, Lotz S, Borden S, Armando AM, Quehenberger O, Temple S, Kosik KS. Glasauer SMK, et al. Among authors: guzman e. Stem Cell Reports. 2022 Sep 13;17(9):2127-2140. doi: 10.1016/j.stemcr.2022.07.011. Epub 2022 Aug 18. Stem Cell Reports. 2022. PMID: 35985329 Free PMC article.
A farnesyltransferase inhibitor activates lysosomes and reduces tau pathology in mice with tauopathy.
Hernandez I, Luna G, Rauch JN, Reis SA, Giroux M, Karch CM, Boctor D, Sibih YE, Storm NJ, Diaz A, Kaushik S, Zekanowski C, Kang AA, Hinman CR, Cerovac V, Guzman E, Zhou H, Haggarty SJ, Goate AM, Fisher SK, Cuervo AM, Kosik KS. Hernandez I, et al. Among authors: guzman e. Sci Transl Med. 2019 Mar 27;11(485):eaat3005. doi: 10.1126/scitranslmed.aat3005. Sci Transl Med. 2019. PMID: 30918111 Free PMC article.
LRP1 is a master regulator of tau uptake and spread.
Rauch JN, Luna G, Guzman E, Audouard M, Challis C, Sibih YE, Leshuk C, Hernandez I, Wegmann S, Hyman BT, Gradinaru V, Kampmann M, Kosik KS. Rauch JN, et al. Among authors: guzman e. Nature. 2020 Apr;580(7803):381-385. doi: 10.1038/s41586-020-2156-5. Epub 2020 Apr 1. Nature. 2020. PMID: 32296178 Free PMC article.
576 results