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Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury.
Tonnus W, Meyer C, Steinebach C, Belavgeni A, von Mässenhausen A, Gonzalez NZ, Maremonti F, Gembardt F, Himmerkus N, Latk M, Locke S, Marschner J, Li W, Short S, Doll S, Ingold I, Proneth B, Daniel C, Kabgani N, Kramann R, Motika S, Hergenrother PJ, Bornstein SR, Hugo C, Becker JU, Amann K, Anders HJ, Kreisel D, Pratt D, Gütschow M, Conrad M, Linkermann A. Tonnus W, et al. Among authors: meyer c. Nat Commun. 2021 Jul 20;12(1):4402. doi: 10.1038/s41467-021-24712-6. Nat Commun. 2021. PMID: 34285231 Free PMC article.
The pathological features of regulated necrosis.
Tonnus W, Meyer C, Paliege A, Belavgeni A, von Mässenhausen A, Bornstein SR, Hugo C, Becker JU, Linkermann A. Tonnus W, et al. Among authors: meyer c. J Pathol. 2019 Apr;247(5):697-707. doi: 10.1002/path.5248. Epub 2019 Feb 25. J Pathol. 2019. PMID: 30714148 Review.
Exquisite sensitivity of adrenocortical carcinomas to induction of ferroptosis.
Belavgeni A, Bornstein SR, von Mässenhausen A, Tonnus W, Stumpf J, Meyer C, Othmar E, Latk M, Kanczkowski W, Kroiss M, Hantel C, Hugo C, Fassnacht M, Ziegler CG, Schally AV, Krone NP, Linkermann A. Belavgeni A, et al. Among authors: meyer c. Proc Natl Acad Sci U S A. 2019 Oct 29;116(44):22269-22274. doi: 10.1073/pnas.1912700116. Epub 2019 Oct 14. Proc Natl Acad Sci U S A. 2019. PMID: 31611400 Free PMC article.
Ferroptosis and Necroptosis in the Kidney.
Belavgeni A, Meyer C, Stumpf J, Hugo C, Linkermann A. Belavgeni A, et al. Among authors: meyer c. Cell Chem Biol. 2020 Apr 16;27(4):448-462. doi: 10.1016/j.chembiol.2020.03.016. Cell Chem Biol. 2020. PMID: 32302582 Free article. Review.
Mechanisms and Models of Kidney Tubular Necrosis and Nephron Loss.
Maremonti F, Meyer C, Linkermann A. Maremonti F, et al. Among authors: meyer c. J Am Soc Nephrol. 2022 Mar;33(3):472-486. doi: 10.1681/ASN.2021101293. Epub 2022 Jan 12. J Am Soc Nephrol. 2022. PMID: 35022311 Free PMC article. Review.
Dexamethasone sensitizes to ferroptosis by glucocorticoid receptor-induced dipeptidase-1 expression and glutathione depletion.
von Mässenhausen A, Zamora Gonzalez N, Maremonti F, Belavgeni A, Tonnus W, Meyer C, Beer K, Hannani MT, Lau A, Peitzsch M, Hoppenz P, Locke S, Chavakis T, Kramann R, Muruve DA, Hugo C, Bornstein SR, Linkermann A. von Mässenhausen A, et al. Among authors: meyer c. Sci Adv. 2022 Feb 4;8(5):eabl8920. doi: 10.1126/sciadv.abl8920. Epub 2022 Feb 2. Sci Adv. 2022. PMID: 35108055 Free PMC article.
Gasdermin D-deficient mice are hypersensitive to acute kidney injury.
Tonnus W, Maremonti F, Belavgeni A, Latk M, Kusunoki Y, Brucker A, von Mässenhausen A, Meyer C, Locke S, Gembardt F, Beer K, Hoppenz P, Becker JU, Hugo C, Anders HJ, Bornstein SR, Shao F, Linkermann A. Tonnus W, et al. Among authors: meyer c. Cell Death Dis. 2022 Sep 15;13(9):792. doi: 10.1038/s41419-022-05230-9. Cell Death Dis. 2022. PMID: 36109515 Free PMC article.
Treatment with siRNAs is commonly associated with GPX4 up-regulation and target knockdown-independent sensitization to ferroptosis.
von Mässenhausen A, Schlecht MN, Beer K, Maremonti F, Tonnus W, Belavgeni A, Gavali S, Flade K, Riley JS, Zamora Gonzalez N, Brucker A, Becker JN, Tmava M, Meyer C, Peitzsch M, Hugo C, Gembardt F, Angeli JPF, Bornstein SR, Tait SWG, Linkermann A. von Mässenhausen A, et al. Among authors: meyer c. Sci Adv. 2024 Mar 15;10(11):eadk7329. doi: 10.1126/sciadv.adk7329. Epub 2024 Mar 15. Sci Adv. 2024. PMID: 38489367 Free PMC article.
Anti-ferroptotic mechanism of IL4i1-mediated amino acid metabolism.
Zeitler L, Fiore A, Meyer C, Russier M, Zanella G, Suppmann S, Gargaro M, Sidhu SS, Seshagiri S, Ohnmacht C, Köcher T, Fallarino F, Linkermann A, Murray PJ. Zeitler L, et al. Among authors: meyer c. Elife. 2021 Mar 1;10:e64806. doi: 10.7554/eLife.64806. Elife. 2021. PMID: 33646117 Free PMC article.
5,510 results