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Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury.
Tonnus W, Meyer C, Steinebach C, Belavgeni A, von Mässenhausen A, Gonzalez NZ, Maremonti F, Gembardt F, Himmerkus N, Latk M, Locke S, Marschner J, Li W, Short S, Doll S, Ingold I, Proneth B, Daniel C, Kabgani N, Kramann R, Motika S, Hergenrother PJ, Bornstein SR, Hugo C, Becker JU, Amann K, Anders HJ, Kreisel D, Pratt D, Gütschow M, Conrad M, Linkermann A. Tonnus W, et al. Among authors: von massenhausen a. Nat Commun. 2021 Jul 20;12(1):4402. doi: 10.1038/s41467-021-24712-6. Nat Commun. 2021. PMID: 34285231 Free PMC article.
The pathological features of regulated necrosis.
Tonnus W, Meyer C, Paliege A, Belavgeni A, von Mässenhausen A, Bornstein SR, Hugo C, Becker JU, Linkermann A. Tonnus W, et al. Among authors: von massenhausen a. J Pathol. 2019 Apr;247(5):697-707. doi: 10.1002/path.5248. Epub 2019 Feb 25. J Pathol. 2019. PMID: 30714148 Review.
Gasdermin D-deficient mice are hypersensitive to acute kidney injury.
Tonnus W, Maremonti F, Belavgeni A, Latk M, Kusunoki Y, Brucker A, von Mässenhausen A, Meyer C, Locke S, Gembardt F, Beer K, Hoppenz P, Becker JU, Hugo C, Anders HJ, Bornstein SR, Shao F, Linkermann A. Tonnus W, et al. Among authors: von massenhausen a. Cell Death Dis. 2022 Sep 15;13(9):792. doi: 10.1038/s41419-022-05230-9. Cell Death Dis. 2022. PMID: 36109515 Free PMC article.
Immunological consequences of kidney cell death.
Sarhan M, von Mässenhausen A, Hugo C, Oberbauer R, Linkermann A. Sarhan M, et al. Among authors: von massenhausen a. Cell Death Dis. 2018 Jan 25;9(2):114. doi: 10.1038/s41419-017-0057-9. Cell Death Dis. 2018. PMID: 29371597 Free PMC article. Review.
Phenytoin inhibits necroptosis.
von Mässenhausen A, Tonnus W, Himmerkus N, Parmentier S, Saleh D, Rodriguez D, Ousingsawat J, Ang RL, Weinberg JM, Sanz AB, Ortiz A, Zierleyn A, Becker JU, Baratte B, Desban N, Bach S, Schiessl IM, Nogusa S, Balachandran S, Anders HJ, Ting AT, Bleich M, Degterev A, Kunzelmann K, Bornstein SR, Green DR, Hugo C, Linkermann A. von Mässenhausen A, et al. Cell Death Dis. 2018 Mar 2;9(3):359. doi: 10.1038/s41419-018-0394-3. Cell Death Dis. 2018. PMID: 29500402 Free PMC article.
Exquisite sensitivity of adrenocortical carcinomas to induction of ferroptosis.
Belavgeni A, Bornstein SR, von Mässenhausen A, Tonnus W, Stumpf J, Meyer C, Othmar E, Latk M, Kanczkowski W, Kroiss M, Hantel C, Hugo C, Fassnacht M, Ziegler CG, Schally AV, Krone NP, Linkermann A. Belavgeni A, et al. Among authors: von massenhausen a. Proc Natl Acad Sci U S A. 2019 Oct 29;116(44):22269-22274. doi: 10.1073/pnas.1912700116. Epub 2019 Oct 14. Proc Natl Acad Sci U S A. 2019. PMID: 31611400 Free PMC article.
Dexamethasone sensitizes to ferroptosis by glucocorticoid receptor-induced dipeptidase-1 expression and glutathione depletion.
von Mässenhausen A, Zamora Gonzalez N, Maremonti F, Belavgeni A, Tonnus W, Meyer C, Beer K, Hannani MT, Lau A, Peitzsch M, Hoppenz P, Locke S, Chavakis T, Kramann R, Muruve DA, Hugo C, Bornstein SR, Linkermann A. von Mässenhausen A, et al. Sci Adv. 2022 Feb 4;8(5):eabl8920. doi: 10.1126/sciadv.abl8920. Epub 2022 Feb 2. Sci Adv. 2022. PMID: 35108055 Free PMC article.
31 results