Dayal N - Search Results

1

3H-Pyrazolo[4,3-f]quinoline-Based Kinase Inhibitors Inhibit the Proliferation of Acute Myeloid Leukemia Cells In Vivo.

Dayal N, Řezníčková E, Hernandez DE, Peřina M, Torregrosa-Allen S, Elzey BD, Škerlová J, Ajani H, Djukic S, Vojáčková V, Lepšík M, Řezáčová P, Kryštof V, Jorda R, Sintim HO. Dayal N, et al. J Med Chem. 2021 Aug 12;64(15):10981-10996. doi: 10.1021/acs.jmedchem.1c00330. Epub 2021 Jul 21. J Med Chem. 2021. PMID: 34288692

2

Dual FLT3/TOPK inhibitor with activity against FLT3-ITD secondary mutations potently inhibits acute myeloid leukemia cell lines.

Dayal N, Opoku-Temeng C, Hernandez DE, Sooreshjani MA, Carter-Cooper BA, Lapidus RG, Sintim HO. Dayal N, et al. Future Med Chem. 2018 Apr 1;10(7):823-835. doi: 10.4155/fmc-2017-0298. Epub 2018 Feb 13. Future Med Chem. 2018. PMID: 29437468 Free PMC article.

3

Tetrahydro-3H-pyrazolo[4,3-a]phenanthridine-based CDK inhibitor.

Opoku-Temeng C , Dayal N , Hernandez DE , Naganna N , Sintim HO . Opoku-Temeng C , et al. Among authors: dayal n. Chem Commun (Camb). 2018 May 1;54(36):4521-4524. doi: 10.1039/c8cc01154k. Chem Commun (Camb). 2018. PMID: 29629444

4

3H-pyrazolo[4,3-f]quinoline haspin kinase inhibitors and anticancer properties.

Opoku-Temeng C, Dayal N, Aflaki Sooreshjani M, Sintim HO. Opoku-Temeng C, et al. Among authors: dayal n. Bioorg Chem. 2018 Aug;78:418-426. doi: 10.1016/j.bioorg.2018.03.031. Epub 2018 Apr 17. Bioorg Chem. 2018. PMID: 29698892 Free PMC article.

5

N-(1,3,4-oxadiazol-2-yl)benzamide analogs, bacteriostatic agents against methicillin- and vancomycin-resistant bacteria.

Opoku-Temeng C, Naclerio GA, Mohammad H, Dayal N, Abutaleb NS, Seleem MN, Sintim HO. Opoku-Temeng C, et al. Among authors: dayal n. Eur J Med Chem. 2018 Jul 15;155:797-805. doi: 10.1016/j.ejmech.2018.06.023. Epub 2018 Jun 15. Eur J Med Chem. 2018. PMID: 29957525

6

Berenil Binds Tightly to Parallel and Mixed Parallel/Antiparallel G-Quadruplex Motifs with Varied Thermodynamic Signatures.

Mikek CG, West SJ, Gwin JC, Dayal N, Sintim HO, Lewis EA. Mikek CG, et al. Among authors: dayal n. ACS Omega. 2018 Sep 30;3(9):11582-11591. doi: 10.1021/acsomega.8b01621. Epub 2018 Sep 21. ACS Omega. 2018. PMID: 30320266 Free PMC article.

7

Potently inhibiting cancer cell migration with novel 3H-pyrazolo[4,3-f]quinoline boronic acid ROCK inhibitors.

Dayal N, Mikek CG, Hernandez D, Naclerio GA, Yin Chu EF, Carter-Cooper BA, Lapidus RG, Sintim HO. Dayal N, et al. Eur J Med Chem. 2019 Oct 15;180:449-456. doi: 10.1016/j.ejmech.2019.06.089. Epub 2019 Jun 29. Eur J Med Chem. 2019. PMID: 31330446

8

Inhibitors of Intracellular Gram-Positive Bacterial Growth Synthesized via Povarov-Doebner Reactions.

Dayal N, Opoku-Temeng C, Mohammad H, Abutaleb NS, Hernandez D, Onyedibe KI, Wang M, Zeller M, Seleem MN, Sintim HO. Dayal N, et al. ACS Infect Dis. 2019 Nov 8;5(11):1820-1830. doi: 10.1021/acsinfecdis.9b00022. Epub 2019 Sep 25. ACS Infect Dis. 2019. PMID: 31512848

9

HSD1787, a Tetrahydro-3H-Pyrazolo[4,3-f]Quinoline Compound Synthesized via Povarov Reaction, Potently Inhibits Proliferation of Cancer Cell Lines at Nanomolar Concentrations.

Dayal N, Wang M, Sintim HO. Dayal N, et al. ACS Omega. 2020 Sep 11;5(37):23799-23807. doi: 10.1021/acsomega.0c03001. eCollection 2020 Sep 22. ACS Omega. 2020. PMID: 32984700 Free PMC article.

10

SF₅- and SCF₃-substituted tetrahydroquinoline compounds as potent bactericidal agents against multidrug-resistant persister Gram-positive bacteria.

Onyedibe KI, Dayal N, Sintim HO. Onyedibe KI, et al. Among authors: dayal n. RSC Med Chem. 2021 Aug 10;12(11):1879-1893. doi: 10.1039/d1md00211b. eCollection 2021 Nov 17. RSC Med Chem. 2021. PMID: 34825185 Free PMC article.

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