Schihada H - Search Results

1

A Versatile Sub-Nanomolar Fluorescent Ligand Enables NanoBRET Binding Studies and Single-Molecule Microscopy at the Histamine H₃ Receptor.

Rosier N, Grätz L, Schihada H, Möller J, Işbilir A, Humphrys LJ, Nagl M, Seibel U, Lohse MJ, Pockes S. Rosier N, et al. Among authors: schihada h. J Med Chem. 2021 Aug 12;64(15):11695-11708. doi: 10.1021/acs.jmedchem.1c01089. Epub 2021 Jul 26. J Med Chem. 2021. PMID: 34309390

2

A universal bioluminescence resonance energy transfer sensor design enables high-sensitivity screening of GPCR activation dynamics.

Schihada H, Vandenabeele S, Zabel U, Frank M, Lohse MJ, Maiellaro I. Schihada H, et al. Commun Biol. 2018 Aug 7;1:105. doi: 10.1038/s42003-018-0072-0. eCollection 2018. Commun Biol. 2018. PMID: 30271985 Free PMC article.

3

Development of a Conformational Histamine H₃ Receptor Biosensor for the Synchronous Screening of Agonists and Inverse Agonists.

Schihada H, Ma X, Zabel U, Vischer HF, Schulte G, Leurs R, Pockes S, Lohse MJ. Schihada H, et al. ACS Sens. 2020 Jun 26;5(6):1734-1742. doi: 10.1021/acssensors.0c00397. Epub 2020 May 28. ACS Sens. 2020. PMID: 32397705 Free PMC article.

4

Bioluminescence in G Protein-Coupled Receptors Drug Screening Using Nanoluciferase and Halo-Tag Technology.

Schihada H, Nemec K, Lohse MJ, Maiellaro I. Schihada H, et al. Methods Mol Biol. 2021;2268:137-147. doi: 10.1007/978-1-0716-1221-7_9. Methods Mol Biol. 2021. PMID: 34085266

5

Functional modulation of PTH1R activation and signaling by RAMP2.

Nemec K, Schihada H, Kleinau G, Zabel U, Grushevskyi EO, Scheerer P, Lohse MJ, Maiellaro I. Nemec K, et al. Among authors: schihada h. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2122037119. doi: 10.1073/pnas.2122037119. Epub 2022 Aug 1. Proc Natl Acad Sci U S A. 2022. PMID: 35914163 Free PMC article.

6

Isoforms of GPR35 have distinct extracellular N-termini that allosterically modify receptor-transducer coupling and mediate intracellular pathway bias.

Schihada H, Klompstra TM, Humphrys LJ, Cervenka I, Dadvar S, Kolb P, Ruas JL, Schulte G. Schihada H, et al. J Biol Chem. 2022 Sep;298(9):102328. doi: 10.1016/j.jbc.2022.102328. Epub 2022 Aug 4. J Biol Chem. 2022. PMID: 35933013 Free PMC article.

7

WNT stimulation induces dynamic conformational changes in the Frizzled-Dishevelled interaction.

Bowin CF, Kozielewicz P, Grätz L, Kowalski-Jahn M, Schihada H, Schulte G. Bowin CF, et al. Among authors: schihada h. Sci Signal. 2023 Apr 4;16(779):eabo4974. doi: 10.1126/scisignal.abo4974. Epub 2023 Apr 4. Sci Signal. 2023. PMID: 37014927

8

Development of Fluorescent AF64394 Analogues Enables Real-Time Binding Studies for the Orphan Class A GPCR GPR3.

Bresinsky M, Shahraki A, Kolb P, Pockes S, Schihada H. Bresinsky M, et al. Among authors: schihada h. J Med Chem. 2023 Nov 9;66(21):15025-15041. doi: 10.1021/acs.jmedchem.3c01707. Epub 2023 Oct 31. J Med Chem. 2023. PMID: 37907069 Free PMC article.

9

Shedding Light on the D₁ -Like Receptors: A Fluorescence-Based Toolbox for Visualization of the D₁ and D₅ Receptors.

Rosier N, Mönnich D, Nagl M, Schihada H, Sirbu A, Konar N, Reyes-Resina I, Navarro G, Franco R, Kolb P, Annibale P, Pockes S. Rosier N, et al. Among authors: schihada h. Chembiochem. 2024 Jan 15;25(2):e202300658. doi: 10.1002/cbic.202300658. Epub 2023 Nov 20. Chembiochem. 2024. PMID: 37983731

10

eGFP-tagged Wnt-3a enables functional analysis of Wnt trafficking and signaling and kinetic assessment of Wnt binding to full-length Frizzled.

Wesslowski J, Kozielewicz P, Wang X, Cui H, Schihada H, Kranz D, Karuna M P, Levkin P, Gross JC, Boutros M, Schulte G, Davidson G. Wesslowski J, et al. Among authors: schihada h. J Biol Chem. 2020 Jun 26;295(26):8759-8774. doi: 10.1074/jbc.RA120.012892. Epub 2020 May 7. J Biol Chem. 2020. PMID: 32381507 Free PMC article.

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