de Koning HP - Search Results

1

Divergent metabolism between Trypanosoma congolense and Trypanosoma brucei results in differential sensitivity to metabolic inhibition.

Steketee PC, Dickie EA, Iremonger J, Crouch K, Paxton E, Jayaraman S, Alfituri OA, Awuah-Mensah G, Ritchie R, Schnaufer A, Rowan T, de Koning HP, Gadelha C, Wickstead B, Barrett MP, Morrison LJ. Steketee PC, et al. Among authors: de koning hp. PLoS Pathog. 2021 Jul 26;17(7):e1009734. doi: 10.1371/journal.ppat.1009734. eCollection 2021 Jul. PLoS Pathog. 2021. PMID: 34310651 Free PMC article.

2

A drug resistance determinant in Trypanosoma brucei.

Carter NS, Barrett MP, de Koning HP. Carter NS, et al. Among authors: de koning hp. Trends Microbiol. 1999 Dec;7(12):469-71. doi: 10.1016/s0966-842x(99)01643-1. Trends Microbiol. 1999. PMID: 10603477 Review. No abstract available.

3

Further evidence for a link between melarsoprol resistance and P2 transporter function in African trypanosomes.

de Koning HP, MacLeod A, Barrett MP, Cover B, Jarvis SM. de Koning HP, et al. Mol Biochem Parasitol. 2000 Feb 25;106(1):181-5. doi: 10.1016/s0166-6851(99)00206-6. Mol Biochem Parasitol. 2000. PMID: 10743623 No abstract available.

4

Uptake of pentamidine in Trypanosoma brucei brucei is mediated by three distinct transporters: implications for cross-resistance with arsenicals.

De Koning HP. De Koning HP. Mol Pharmacol. 2001 Mar;59(3):586-92. doi: 10.1124/mol.59.3.586. Mol Pharmacol. 2001. PMID: 11179454

5

Uptake of pentamidine in Trypanosoma brucei brucei is mediated by the P2 adenosine transporter and at least one novel, unrelated transporter.

de Koning HP, Jarvis SM. de Koning HP, et al. Acta Trop. 2001 Dec 21;80(3):245-50. doi: 10.1016/s0001-706x(01)00177-2. Acta Trop. 2001. PMID: 11700182

6

Cloning, heterologous expression, and in situ characterization of the first high affinity nucleobase transporter from a protozoan.

Burchmore RJ, Wallace LJ, Candlish D, Al-Salabi MI, Beal PR, Barrett MP, Baldwin SA, de Koning HP. Burchmore RJ, et al. Among authors: de koning hp. J Biol Chem. 2003 Jun 27;278(26):23502-7. doi: 10.1074/jbc.M301252200. Epub 2003 Apr 21. J Biol Chem. 2003. PMID: 12707261 Free article.

7

Pentamidine uptake and resistance in pathogenic protozoa: past, present and future.

Bray PG, Barrett MP, Ward SA, de Koning HP. Bray PG, et al. Among authors: de koning hp. Trends Parasitol. 2003 May;19(5):232-9. doi: 10.1016/s1471-4922(03)00069-2. Trends Parasitol. 2003. PMID: 12763430 Review.

8

Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei.

Matovu E, Stewart ML, Geiser F, Brun R, Mäser P, Wallace LJ, Burchmore RJ, Enyaru JC, Barrett MP, Kaminsky R, Seebeck T, de Koning HP. Matovu E, et al. Among authors: de koning hp. Eukaryot Cell. 2003 Oct;2(5):1003-8. doi: 10.1128/EC.2.5.1003-1008.2003. Eukaryot Cell. 2003. PMID: 14555482 Free PMC article.

9

The trypanocide diminazene aceturate is accumulated predominantly through the TbAT1 purine transporter: additional insights on diamidine resistance in african trypanosomes.

de Koning HP, Anderson LF, Stewart M, Burchmore RJ, Wallace LJ, Barrett MP. de Koning HP, et al. Antimicrob Agents Chemother. 2004 May;48(5):1515-9. doi: 10.1128/AAC.48.5.1515-1519.2004. Antimicrob Agents Chemother. 2004. PMID: 15105099 Free PMC article.

10

Selective transport of a new class of purine antimetabolites by the protozoan parasite Trypanosoma brucei.

Wallace LJ, Candlish D, Hagos A, Seley KL, de Koning HP. Wallace LJ, et al. Among authors: de koning hp. Nucleosides Nucleotides Nucleic Acids. 2004 Oct;23(8-9):1441-4. doi: 10.1081/NCN-200027660. Nucleosides Nucleotides Nucleic Acids. 2004. PMID: 15571273

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