Chiou WJ - Search Results

1

Quantitation of Plasma Membrane Drug Transporters in Kidney Tissue and Cell Lines Using a Novel Proteomic Approach Enabled a Prospective Prediction of Metformin Disposition.

Kikuchi R, Chiou WJ, Durbin KR, Savaryn JP, Ma J, Emami Riedmaier A, de Morais SM, Jenkins GJ, Bow DAJ. Kikuchi R, et al. Among authors: chiou wj. Drug Metab Dispos. 2021 Oct;49(10):938-946. doi: 10.1124/dmd.121.000487. Epub 2021 Jul 30. Drug Metab Dispos. 2021. PMID: 34330717

2

Prediction of clinical drug-drug interactions of veliparib (ABT-888) with human renal transporters (OAT1, OAT3, OCT2, MATE1, and MATE2K).

Kikuchi R, Lao Y, Bow DA, Chiou WJ, Andracki ME, Carr RA, Voorman RL, De Morais SM. Kikuchi R, et al. Among authors: chiou wj. J Pharm Sci. 2013 Dec;102(12):4426-32. doi: 10.1002/jps.23737. Epub 2013 Oct 2. J Pharm Sci. 2013. PMID: 24122511

3

Validation of a total IC₅₀ method which enables in vitro assessment of transporter inhibition under semi-physiological conditions.

Kikuchi R, Peterkin VC, Chiou WJ, de Morais SM, Bow DAJ. Kikuchi R, et al. Among authors: chiou wj. Xenobiotica. 2017 Sep;47(9):825-832. doi: 10.1080/00498254.2016.1233372. Epub 2016 Oct 3. Xenobiotica. 2017. PMID: 27609543

4

No Inhibition of MATE1/2K-Mediated Renal Creatinine Secretion Predicted With Ritonavir or Cobicistat.

Kikuchi R, Chiou WJ, Kasai MA, de Morais SM, Bow DAJ. Kikuchi R, et al. Among authors: chiou wj. J Pharm Sci. 2019 Sep;108(9):3118-3123. doi: 10.1016/j.xphs.2019.04.023. Epub 2019 Apr 26. J Pharm Sci. 2019. PMID: 31034908

5

In vitro OATP1B1 and OATP1B3 inhibition is associated with observations of benign clinical unconjugated hyperbilirubinemia.

Chiou WJ, de Morais SM, Kikuchi R, Voorman RL, Li X, Bow DA. Chiou WJ, et al. Xenobiotica. 2014 Mar;44(3):276-82. doi: 10.3109/00498254.2013.820006. Epub 2013 Jul 25. Xenobiotica. 2014. PMID: 23886114

6

Quantitative measurements of corticosteroids in ex vivo samples using on-line SPE-LC/MS/MS.

Gao L, Chiou WJ, Camp HS, Burns DJ, Cheng X. Gao L, et al. Among authors: chiou wj. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Jan 15;877(3):303-10. doi: 10.1016/j.jchromb.2008.12.029. Epub 2008 Dec 24. J Chromatogr B Analyt Technol Biomed Life Sci. 2009. PMID: 19119084

7

Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome.

Cool B, Zinker B, Chiou W, Kifle L, Cao N, Perham M, Dickinson R, Adler A, Gagne G, Iyengar R, Zhao G, Marsh K, Kym P, Jung P, Camp HS, Frevert E. Cool B, et al. Cell Metab. 2006 Jun;3(6):403-16. doi: 10.1016/j.cmet.2006.05.005. Cell Metab. 2006. PMID: 16753576 Free article.

8

Simultaneous quantification of malonyl-CoA and several other short-chain acyl-CoAs in animal tissues by ion-pairing reversed-phase HPLC/MS.

Gao L, Chiou W, Tang H, Cheng X, Camp HS, Burns DJ. Gao L, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Jun 15;853(1-2):303-13. doi: 10.1016/j.jchromb.2007.03.029. Epub 2007 Mar 31. J Chromatogr B Analyt Technol Biomed Life Sci. 2007. PMID: 17442642

9

Discovery and metabolic stabilization of potent and selective 2-amino-N-(adamant-2-yl) acetamide 11beta-hydroxysteroid dehydrogenase type 1 inhibitors.

Rohde JJ, Pliushchev MA, Sorensen BK, Wodka D, Shuai Q, Wang J, Fung S, Monzon KM, Chiou WJ, Pan L, Deng X, Chovan LE, Ramaiya A, Mullally M, Henry RF, Stolarik DF, Imade HM, Marsh KC, Beno DW, Fey TA, Droz BA, Brune ME, Camp HS, Sham HL, Frevert EU, Jacobson PB, Link JT. Rohde JJ, et al. Among authors: chiou wj. J Med Chem. 2007 Jan 11;50(1):149-64. doi: 10.1021/jm0609364. J Med Chem. 2007. PMID: 17201418

10

Adamantane sulfone and sulfonamide 11-beta-HSD1 Inhibitors.

Sorensen B, Winn M, Rohde J, Shuai Q, Wang J, Fung S, Monzon K, Chiou W, Stolarik D, Imade H, Pan L, Deng X, Chovan L, Longenecker K, Judge R, Qin W, Brune M, Camp H, Frevert EU, Jacobson P, Link JT. Sorensen B, et al. Bioorg Med Chem Lett. 2007 Jan 15;17(2):527-32. doi: 10.1016/j.bmcl.2006.10.008. Epub 2006 Oct 7. Bioorg Med Chem Lett. 2007. PMID: 17070044

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