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PolyG-DS: An ultrasensitive polyguanine tract-profiling method to detect clonal expansions and trace cell lineage.
Zhang Y, Kohrn BF, Yang M, Nachmanson D, Soong TR, Lee IH, Tao Y, Clevers H, Swisher EM, Brentnall TA, Loeb LA, Kennedy SR, Salk JJ, Naxerova K, Risques RA. Zhang Y, et al. Among authors: kohrn bf. Proc Natl Acad Sci U S A. 2021 Aug 3;118(31):e2023373118. doi: 10.1073/pnas.2023373118. Proc Natl Acad Sci U S A. 2021. PMID: 34330826 Free PMC article.
Detecting ultralow-frequency mutations by Duplex Sequencing.
Kennedy SR, Schmitt MW, Fox EJ, Kohrn BF, Salk JJ, Ahn EH, Prindle MJ, Kuong KJ, Shen JC, Risques RA, Loeb LA. Kennedy SR, et al. Among authors: kohrn bf. Nat Protoc. 2014 Nov;9(11):2586-606. doi: 10.1038/nprot.2014.170. Epub 2014 Oct 9. Nat Protoc. 2014. PMID: 25299156 Free PMC article.
Volatility of Mutator Phenotypes at Single Cell Resolution.
Kennedy SR, Schultz EM, Chappell TM, Kohrn B, Knowels GM, Herr AJ. Kennedy SR, et al. PLoS Genet. 2015 Apr 13;11(4):e1005151. doi: 10.1371/journal.pgen.1005151. eCollection 2015 Apr. PLoS Genet. 2015. PMID: 25868109 Free PMC article.
Targeted genome fragmentation with CRISPR/Cas9 enables fast and efficient enrichment of small genomic regions and ultra-accurate sequencing with low DNA input (CRISPR-DS).
Nachmanson D, Lian S, Schmidt EK, Hipp MJ, Baker KT, Zhang Y, Tretiakova M, Loubet-Senear K, Kohrn BF, Salk JJ, Kennedy SR, Risques RA. Nachmanson D, et al. Among authors: kohrn bf. Genome Res. 2018 Oct;28(10):1589-1599. doi: 10.1101/gr.235291.118. Epub 2018 Sep 19. Genome Res. 2018. PMID: 30232196 Free PMC article.
A replication-linked mutational gradient drives somatic mutation accumulation and influences germline polymorphisms and genome composition in mitochondrial DNA.
Sanchez-Contreras M, Sweetwyne MT, Kohrn BF, Tsantilas KA, Hipp MJ, Schmidt EK, Fredrickson J, Whitson JA, Campbell MD, Rabinovitch PS, Marcinek DJ, Kennedy SR. Sanchez-Contreras M, et al. Among authors: kohrn bf. Nucleic Acids Res. 2021 Nov 8;49(19):11103-11118. doi: 10.1093/nar/gkab901. Nucleic Acids Res. 2021. PMID: 34614167 Free PMC article.
23 results