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Malaria parasites both repress host CXCL10 and use it as a cue for growth acceleration.
Ofir-Birin Y, Ben Ami Pilo H, Cruz Camacho A, Rudik A, Rivkin A, Revach OY, Nir N, Block Tamin T, Abou Karam P, Kiper E, Peleg Y, Nevo R, Solomon A, Havkin-Solomon T, Rojas A, Rotkopf R, Porat Z, Avni D, Schwartz E, Zillinger T, Hartmann G, Di Pizio A, Quashie NB, Dikstein R, Gerlic M, Torrecilhas AC, Levy C, Nolte-'t Hoen ENM, Bowie AG, Regev-Rudzki N. Ofir-Birin Y, et al. Among authors: abou karam p. Nat Commun. 2021 Aug 11;12(1):4851. doi: 10.1038/s41467-021-24997-7. Nat Commun. 2021. PMID: 34381047 Free PMC article.
Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors.
Sisquella X, Ofir-Birin Y, Pimentel MA, Cheng L, Abou Karam P, Sampaio NG, Penington JS, Connolly D, Giladi T, Scicluna BJ, Sharples RA, Waltmann A, Avni D, Schwartz E, Schofield L, Porat Z, Hansen DS, Papenfuss AT, Eriksson EM, Gerlic M, Hill AF, Bowie AG, Regev-Rudzki N. Sisquella X, et al. Among authors: abou karam p. Nat Commun. 2017 Dec 7;8(1):1985. doi: 10.1038/s41467-017-02083-1. Nat Commun. 2017. PMID: 29215015 Free PMC article.
Histamine releasing factor and elongation factor 1 alpha secreted via malaria parasites extracellular vesicles promote immune evasion by inhibiting specific T cell responses.
Demarta-Gatsi C, Rivkin A, Di Bartolo V, Peronet R, Ding S, Commere PH, Guillonneau F, Bellalou J, Brûlé S, Abou Karam P, Cohen SR, Lagache T, Janse CJ, Regev-Rudzki N, Mécheri S. Demarta-Gatsi C, et al. Among authors: abou karam p. Cell Microbiol. 2019 Jul;21(7):e13021. doi: 10.1111/cmi.13021. Epub 2019 Apr 1. Cell Microbiol. 2019. PMID: 30835870
Quantitative identification of senescent cells in aging and disease.
Biran A, Zada L, Abou Karam P, Vadai E, Roitman L, Ovadya Y, Porat Z, Krizhanovsky V. Biran A, et al. Among authors: abou karam p. Aging Cell. 2017 Aug;16(4):661-671. doi: 10.1111/acel.12592. Epub 2017 Apr 28. Aging Cell. 2017. PMID: 28455874 Free PMC article.
14 results