Smith NP - Search Results

1

Clonally expanded, GPR15-expressing pathogenic effector T_H2 cells are associated with eosinophilic esophagitis.

Morgan DM, Ruiter B, Smith NP, Tu AA, Monian B, Stone BE, Virk-Hundal N, Yuan Q, Shreffler WG, Love JC. Morgan DM, et al. Among authors: smith np. Sci Immunol. 2021 Aug 13;6(62):eabi5586. doi: 10.1126/sciimmunol.abi5586. Sci Immunol. 2021. PMID: 34389613 Free PMC article.

2

Data-driven programmatic approach to analysis of basophil activation tests.

Patil SU, Calatroni A, Schneider M, Steinbrecher J, Smith N, Washburn C, Ma A, Shreffler WG. Patil SU, et al. Cytometry B Clin Cytom. 2018 Jul;94(4):667-673. doi: 10.1002/cyto.b.21537. Epub 2017 Jul 5. Cytometry B Clin Cytom. 2018. PMID: 28618453 Free PMC article.

3

Designer covalent heterobivalent inhibitors prevent IgE-dependent responses to peanut allergen.

Deak PE, Kim B, Abdul Qayum A, Shin J, Vitalpur G, Kloepfer KM, Turner MJ, Smith N, Shreffler WG, Kiziltepe T, Kaplan MH, Bilgicer B. Deak PE, et al. Proc Natl Acad Sci U S A. 2019 Apr 30;116(18):8966-8974. doi: 10.1073/pnas.1820417116. Epub 2019 Apr 8. Proc Natl Acad Sci U S A. 2019. PMID: 30962381 Free PMC article.

4

Early decrease in basophil sensitivity to Ara h 2 precedes sustained unresponsiveness after peanut oral immunotherapy.

Patil SU, Steinbrecher J, Calatroni A, Smith N, Ma A, Ruiter B, Virkud Y, Schneider M, Shreffler WG. Patil SU, et al. J Allergy Clin Immunol. 2019 Nov;144(5):1310-1319.e4. doi: 10.1016/j.jaci.2019.07.028. Epub 2019 Aug 1. J Allergy Clin Immunol. 2019. PMID: 31377342 Free PMC article. Clinical Trial.

5

Expansion of the CD4⁺ effector T-cell repertoire characterizes peanut-allergic patients with heightened clinical sensitivity.

Ruiter B, Smith NP, Monian B, Tu AA, Fleming E, Virkud YV, Patil SU, Whittaker CA, Love JC, Shreffler WG. Ruiter B, et al. Among authors: smith np. J Allergy Clin Immunol. 2020 Jan;145(1):270-282. doi: 10.1016/j.jaci.2019.09.033. Epub 2019 Oct 22. J Allergy Clin Immunol. 2020. PMID: 31654649 Free PMC article. Clinical Trial.

6

Peanut protein acts as a T_H2 adjuvant by inducing RALDH2 in human antigen-presenting cells.

Ruiter B, Smith NP, Fleming E, Patil SU, Hurlburt BK, Maleki SJ, Shreffler WG. Ruiter B, et al. Among authors: smith np. J Allergy Clin Immunol. 2021 Jul;148(1):182-194.e4. doi: 10.1016/j.jaci.2020.11.047. Epub 2020 Dec 27. J Allergy Clin Immunol. 2021. PMID: 33378690 Free PMC article.

7

Identification of antigen-specific TCR sequences based on biological and statistical enrichment in unselected individuals.

Smith NP, Ruiter B, Virkud YV, Tu AA, Monian B, Moon JJ, Love JC, Shreffler WG. Smith NP, et al. JCI Insight. 2021 Jul 8;6(13):e140028. doi: 10.1172/jci.insight.140028. JCI Insight. 2021. PMID: 34032640 Free PMC article.

8

Peanut oral immunotherapy differentially suppresses clonally distinct subsets of T helper cells.

Monian B, Tu AA, Ruiter B, Morgan DM, Petrossian PM, Smith NP, Gierahn TM, Ginder JH, Shreffler WG, Love JC. Monian B, et al. Among authors: smith np. J Clin Invest. 2022 Jan 18;132(2):e150634. doi: 10.1172/JCI150634. J Clin Invest. 2022. PMID: 34813505 Free PMC article. Clinical Trial.

9

A human model of asthma exacerbation reveals transcriptional programs and cell circuits specific to allergic asthma.

Alladina J, Smith NP, Kooistra T, Slowikowski K, Kernin IJ, Deguine J, Keen HL, Manakongtreecheep K, Tantivit J, Rahimi RA, Sheng SL, Nguyen ND, Haring AM, Giacona FL, Hariri LP, Xavier RJ, Luster AD, Villani AC, Cho JL, Medoff BD. Alladina J, et al. Among authors: smith np. Sci Immunol. 2023 May 12;8(83):eabq6352. doi: 10.1126/sciimmunol.abq6352. Epub 2023 May 5. Sci Immunol. 2023. PMID: 37146132 Free PMC article.

10

Metabolomics of IgE-Mediated Food Allergy and Oral Immunotherapy Outcomes based on Metabolomic Profiling.

Virkud YV, Styles JN, Kelly RS, Patil SU, Ruiter B, Smith NP, Clish C, Wheelock CE, Celedón JC, Litonjua AA, Bunyavanich S, Weiss ST, Baker ES, Lasky-Su JA, Shreffler WG. Virkud YV, et al. Among authors: smith np. medRxiv [Preprint]. 2024 Jun 1:2024.05.31.24308233. doi: 10.1101/2024.05.31.24308233. medRxiv. 2024. Update in: Pediatr Allergy Immunol. 2024 Nov;35(11):e14267. doi: 10.1111/pai.14267 PMID: 38952781 Free PMC article. Updated. Preprint.

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