Wu Y - Search Results

1

Novel quinolone derivatives targeting human dihydroorotate dehydrogenase suppress Ebola virus infection in vitro.

Gong M, Yang Y, Huang Y, Gan T, Wu Y, Gao H, Li Q, Nie J, Huang W, Wang Y, Zhang R, Zhong J, Deng F, Rao Y, Ding Q. Gong M, et al. Among authors: wu y. Antiviral Res. 2021 Oct;194:105161. doi: 10.1016/j.antiviral.2021.105161. Epub 2021 Aug 12. Antiviral Res. 2021. PMID: 34391783

2

[The molecular mechanism of neuronal migration].

Rao Y, Wu Y. Rao Y, et al. Among authors: wu y. Sheng Li Ke Xue Jin Zhan. 2000 Jul;31(3):198-204. Sheng Li Ke Xue Jin Zhan. 2000. PMID: 12545704 Review. Chinese.

3

Target Elucidation by Cocrystal Structures of NADH-Ubiquinone Oxidoreductase of Plasmodium falciparum (PfNDH2) with Small Molecule To Eliminate Drug-Resistant Malaria.

Yang Y, Yu Y, Li X, Li J, Wu Y, Yu J, Ge J, Huang Z, Jiang L, Rao Y, Yang M. Yang Y, et al. Among authors: wu y. J Med Chem. 2017 Mar 9;60(5):1994-2005. doi: 10.1021/acs.jmedchem.6b01733. Epub 2017 Feb 22. J Med Chem. 2017. PMID: 28195463

4

PROTAC-induced BTK degradation as a novel therapy for mutated BTK C481S induced ibrutinib-resistant B-cell malignancies.

Sun Y, Zhao X, Ding N, Gao H, Wu Y, Yang Y, Zhao M, Hwang J, Song Y, Liu W, Rao Y. Sun Y, et al. Among authors: wu y. Cell Res. 2018 Jul;28(7):779-781. doi: 10.1038/s41422-018-0055-1. Epub 2018 Jun 6. Cell Res. 2018. PMID: 29875397 Free PMC article. No abstract available.

5

Synthesis, Evaluation, and Structure-Activity Relationship Study of Lanosterol Derivatives To Reverse Mutant-Crystallin-Induced Protein Aggregation.

Yang X, Chen XJ, Yang Z, Xi YB, Wang L, Wu Y, Yan YB, Rao Y. Yang X, et al. Among authors: wu y. J Med Chem. 2018 Oct 11;61(19):8693-8706. doi: 10.1021/acs.jmedchem.8b00705. Epub 2018 Sep 24. J Med Chem. 2018. PMID: 30153006

6

Discovery, Optimization, and Target Identification of Novel Potent Broad-Spectrum Antiviral Inhibitors.

Yang Y, Cao L, Gao H, Wu Y, Wang Y, Fang F, Lan T, Lou Z, Rao Y. Yang Y, et al. Among authors: wu y. J Med Chem. 2019 Apr 25;62(8):4056-4073. doi: 10.1021/acs.jmedchem.9b00091. Epub 2019 Apr 12. J Med Chem. 2019. PMID: 30938999

7

PROTACs: great opportunities for academia and industry.

Sun X, Gao H, Yang Y, He M, Wu Y, Song Y, Tong Y, Rao Y. Sun X, et al. Among authors: wu y. Signal Transduct Target Ther. 2019 Dec 24;4:64. doi: 10.1038/s41392-019-0101-6. eCollection 2019. Signal Transduct Target Ther. 2019. PMID: 31885879 Free PMC article. Review.

8

Degradation versus Inhibition: Development of Proteolysis-Targeting Chimeras for Overcoming Statin-Induced Compensatory Upregulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase.

Li MX, Yang Y, Zhao Q, Wu Y, Song L, Yang H, He M, Gao H, Song BL, Luo J, Rao Y. Li MX, et al. Among authors: wu y. J Med Chem. 2020 May 14;63(9):4908-4928. doi: 10.1021/acs.jmedchem.0c00339. Epub 2020 May 4. J Med Chem. 2020. PMID: 32321253

9

FAK-targeting PROTAC as a chemical tool for the investigation of non-enzymatic FAK function in mice.

Gao H, Zheng C, Du J, Wu Y, Sun Y, Han C, Kee K, Rao Y. Gao H, et al. Among authors: wu y. Protein Cell. 2020 Jul;11(7):534-539. doi: 10.1007/s13238-020-00732-8. Protein Cell. 2020. PMID: 32451721 Free PMC article. No abstract available.

10

Design, Synthesis, and Evaluation of Highly Potent FAK-Targeting PROTACs.

Gao H, Wu Y, Sun Y, Yang Y, Zhou G, Rao Y. Gao H, et al. Among authors: wu y. ACS Med Chem Lett. 2019 Oct 22;11(10):1855-1862. doi: 10.1021/acsmedchemlett.9b00372. eCollection 2020 Oct 8. ACS Med Chem Lett. 2019. PMID: 33062164 Free PMC article.

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