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Mechanistic Investigation of Site-specific DNA Methylating Agents Targeting Breast Cancer Cells.
Lowder LL, Powell M, Miller SE, Kishton RJ, Kelly CB, Cribb CB, Mastro-Kishton K, Chelvanambi M, Do PT, Govindapur RR, Wardell SE, McDonnell DP, Bartolotti LJ, Akkaraju GR, Frampton AR, Varadarajan S. Lowder LL, et al. Among authors: mcdonnell dp. J Med Chem. 2021 Sep 9;64(17):12651-12669. doi: 10.1021/acs.jmedchem.1c00615. Epub 2021 Aug 20. J Med Chem. 2021. PMID: 34415160
Glucose metabolism as a target of histone deacetylase inhibitors.
Wardell SE, Ilkayeva OR, Wieman HL, Frigo DE, Rathmell JC, Newgard CB, McDonnell DP. Wardell SE, et al. Among authors: mcdonnell dp. Mol Endocrinol. 2009 Mar;23(3):388-401. doi: 10.1210/me.2008-0179. Epub 2008 Dec 23. Mol Endocrinol. 2009. PMID: 19106193 Free PMC article.
Differential presentation of protein interaction surfaces on the androgen receptor defines the pharmacological actions of bound ligands.
Norris JD, Joseph JD, Sherk AB, Juzumiene D, Turnbull PS, Rafferty SW, Cui H, Anderson E, Fan D, Dye DA, Deng X, Kazmin D, Chang CY, Willson TM, McDonnell DP. Norris JD, et al. Among authors: mcdonnell dp. Chem Biol. 2009 Apr 24;16(4):452-60. doi: 10.1016/j.chembiol.2009.01.016. Chem Biol. 2009. PMID: 19389631 Free PMC article.
27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology.
Nelson ER, Wardell SE, Jasper JS, Park S, Suchindran S, Howe MK, Carver NJ, Pillai RV, Sullivan PM, Sondhi V, Umetani M, Geradts J, McDonnell DP. Nelson ER, et al. Among authors: mcdonnell dp. Science. 2013 Nov 29;342(6162):1094-8. doi: 10.1126/science.1241908. Science. 2013. PMID: 24288332 Free PMC article.
295 results