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Towards next generation antisense oligonucleotides: mesylphosphoramidate modification improves therapeutic index and duration of effect of gapmer antisense oligonucleotides.
Anderson BA, Freestone GC, Low A, De-Hoyos CL, Iii WJD, Østergaard ME, Migawa MT, Fazio M, Wan WB, Berdeja A, Scandalis E, Burel SA, Vickers TA, Crooke ST, Swayze EE, Liang X, Seth PP. Anderson BA, et al. Among authors: scandalis e. Nucleic Acids Res. 2021 Sep 20;49(16):9026-9041. doi: 10.1093/nar/gkab718. Nucleic Acids Res. 2021. PMID: 34417625 Free PMC article.
Antisense oligonucleotides to therapeutically target SARS-CoV-2 infection.
Qiao Y, Wotring JW, Zhang CJ, Jiang X, Xiao L, Watt A, Gattis D, Scandalis E, Freier S, Zheng Y, Pretto CD, Ellison SJ, Swayze EE, Guo S, Sexton JZ, Chinnaiyan AM. Qiao Y, et al. Among authors: scandalis e. PLoS One. 2023 Feb 3;18(2):e0281281. doi: 10.1371/journal.pone.0281281. eCollection 2023. PLoS One. 2023. PMID: 36735698 Free PMC article.