Bush J - Search Results

1

Accelerated first-in-human clinical trial of EIDD-2801/MK-4482 (molnupiravir), a ribonucleoside analog with potent antiviral activity against SARS-CoV-2.

Holman W, Holman W, McIntosh S, Painter W, Painter G, Bush J, Cohen O. Holman W, et al. Among authors: bush j. Trials. 2021 Aug 23;22(1):561. doi: 10.1186/s13063-021-05538-5. Trials. 2021. PMID: 34425873 Free PMC article. Clinical Trial.

2

Human Safety, Tolerability, and Pharmacokinetics of Molnupiravir, a Novel Broad-Spectrum Oral Antiviral Agent with Activity Against SARS-CoV-2.

Painter WP, Holman W, Bush JA, Almazedi F, Malik H, Eraut NCJE, Morin MJ, Szewczyk LJ, Painter GR. Painter WP, et al. Among authors: bush ja. Antimicrob Agents Chemother. 2021 May 1;65(5):e02428-20. doi: 10.1128/AAC.02428-20. Epub 2021 Mar 1. Antimicrob Agents Chemother. 2021. PMID: 33649113 Free PMC article.

3

A phase 1, randomized study to evaluate safety, tolerability, and pharmacokinetics of GDC-3280, a potential novel anti-fibrotic small molecule, in healthy subjects.

Cheung D, Fong A, Ding HT, Cabanski CR, Wang J, Chen Y, Bush J, Harris JM, Pan L. Cheung D, et al. Among authors: bush j. Pulm Pharmacol Ther. 2021 Aug;69:102051. doi: 10.1016/j.pupt.2021.102051. Epub 2021 Jun 21. Pulm Pharmacol Ther. 2021. PMID: 34166834 Free article. Clinical Trial.

4

Safety and efficacy of an extended-release peptide YY analogue for obesity: A randomized, placebo-controlled, phase 1 trial.

Tan TM, Minnion J, Khoo B, Ball LJ, Malviya R, Day E, Fiorentino F, Brindley C, Bush J, Bloom SR. Tan TM, et al. Among authors: bush j. Diabetes Obes Metab. 2021 Jul;23(7):1471-1483. doi: 10.1111/dom.14358. Epub 2021 Mar 9. Diabetes Obes Metab. 2021. PMID: 33606914 Clinical Trial.

5

Mitigation of Initial Cardiodynamic Effects of the S1P₁ Receptor Modulator Ponesimod Using a Novel Up-Titration Regimen.

Juif PE, Hoch M, Vaclavkova A, Krause A, Bush J, Dingemanse J. Juif PE, et al. Among authors: bush j. J Clin Pharmacol. 2017 Mar;57(3):401-410. doi: 10.1002/jcph.820. Epub 2016 Sep 30. J Clin Pharmacol. 2017. PMID: 27558098 Clinical Trial.

6

A phase 1, randomized, open-label, single-dose study to assess the relative bioavailability of a subcutaneous dose of FKB327 when administered using a prefilled syringe, a prefilled auto-injector, or a vial with disposable syringe in healthy subjects.

Bush J, Kawakami K, Muniz R. Bush J, et al. BMC Pharmacol Toxicol. 2019 Dec 30;20(1):87. doi: 10.1186/s40360-019-0376-9. BMC Pharmacol Toxicol. 2019. PMID: 31888742 Free PMC article. Clinical Trial.

7

Cardiac effects of amiselimod compared with fingolimod and placebo: results of a randomised, parallel-group, phase I study in healthy subjects.

Harada T, Wilbraham D, de La Borderie G, Inoue S, Bush J, Camm AJ. Harada T, et al. Among authors: bush j. Br J Clin Pharmacol. 2017 May;83(5):1011-1027. doi: 10.1111/bcp.13203. Epub 2017 Jan 19. Br J Clin Pharmacol. 2017. PMID: 27921320 Free PMC article. Clinical Trial.

8

Characterization of the Pharmacokinetics of Vilaprisan: Bioavailability, Excretion, Biotransformation, and Drug-Drug Interaction Potential.

Schultze-Mosgau MH, Höchel J, Prien O, Zimmermann T, Brooks A, Bush J, Rottmann A. Schultze-Mosgau MH, et al. Among authors: bush j. Clin Pharmacokinet. 2018 Aug;57(8):1001-1015. doi: 10.1007/s40262-017-0607-4. Clin Pharmacokinet. 2018. PMID: 29330782 Free PMC article. Clinical Trial.

9

A randomised, parallel group study to evaluate the safety profile of an electronic vapour product over 12 weeks.

Cravo AS, Bush J, Sharma G, Savioz R, Martin C, Craige S, Walele T. Cravo AS, et al. Among authors: bush j. Regul Toxicol Pharmacol. 2016 Nov 15;81 Suppl 1:S1-S14. doi: 10.1016/j.yrtph.2016.10.003. Epub 2016 Oct 18. Regul Toxicol Pharmacol. 2016. PMID: 27769828 Free article. Clinical Trial.

10

Evaluation of the safety profile of an electronic vapour product used for two years by smokers in a real-life setting.

Walele T, Bush J, Koch A, Savioz R, Martin C, O'Connell G. Walele T, et al. Among authors: bush j. Regul Toxicol Pharmacol. 2018 Feb;92:226-238. doi: 10.1016/j.yrtph.2017.12.010. Epub 2017 Dec 14. Regul Toxicol Pharmacol. 2018. PMID: 29248487 Free article. Clinical Trial.

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