Niegisch G - Search Results

1

CTLA4 promoter hypomethylation is a negative prognostic biomarker at initial diagnosis but predicts response and favorable outcome to anti-PD-1 based immunotherapy in clear cell renal cell carcinoma.

Klümper N, Ralser DJ, Zarbl R, Schlack K, Schrader AJ, Rehlinghaus M, Hoffmann MJ, Niegisch G, Uhlig A, Trojan L, Steinestel J, Steinestel K, Wirtz RM, Sikic D, Eckstein M, Kristiansen G, Toma M, Hölzel M, Ritter M, Strieth S, Ellinger J, Dietrich D. Klümper N, et al. Among authors: niegisch g. J Immunother Cancer. 2021 Aug;9(8):e002949. doi: 10.1136/jitc-2021-002949. J Immunother Cancer. 2021. PMID: 34446578 Free PMC article.

2

Elicitation of Health State Utilities Associated with Progression from Bacillus Calmette-Guerin (BCG) Unresponsive Non-muscle Invasive Bladder Cancer (NMIBC).

Cooper OAE, Ghatnekar O, Piglowska N, Smith CA, Swinburn P, Catto JWF, Niegisch G, Jakobsen JS. Cooper OAE, et al. Among authors: niegisch g. Pharmacoecon Open. 2023 May;7(3):469-477. doi: 10.1007/s41669-023-00392-4. Epub 2023 Feb 3. Pharmacoecon Open. 2023. PMID: 36737511 Free PMC article.

3

Limited efficacy of specific HDAC6 inhibition in urothelial cancer cells.

Rosik L, Niegisch G, Fischer U, Jung M, Schulz WA, Hoffmann MJ. Rosik L, et al. Among authors: niegisch g. Cancer Biol Ther. 2014 Jun 1;15(6):742-57. doi: 10.4161/cbt.28469. Epub 2014 Mar 11. Cancer Biol Ther. 2014. PMID: 24618845 Free PMC article.

4

Histone deacetylase 8 is deregulated in urothelial cancer but not a target for efficient treatment.

Lehmann M, Hoffmann MJ, Koch A, Ulrich SM, Schulz WA, Niegisch G. Lehmann M, et al. Among authors: niegisch g. J Exp Clin Cancer Res. 2014 Jul 10;33(1):59. doi: 10.1186/s13046-014-0059-8. J Exp Clin Cancer Res. 2014. PMID: 25011684 Free PMC article.

5

Canonical Notch signalling is inactive in urothelial carcinoma.

Greife A, Jankowiak S, Steinbring J, Nikpour P, Niegisch G, Hoffmann MJ, Schulz WA. Greife A, et al. Among authors: niegisch g. BMC Cancer. 2014 Aug 29;14:628. doi: 10.1186/1471-2407-14-628. BMC Cancer. 2014. PMID: 25167871 Free PMC article.

6

Epigenetics of urothelial carcinoma.

Schulz WA, Koutsogiannouli EA, Niegisch G, Hoffmann MJ. Schulz WA, et al. Among authors: niegisch g. Methods Mol Biol. 2015;1238:183-215. doi: 10.1007/978-1-4939-1804-1_10. Methods Mol Biol. 2015. PMID: 25421661 Review.

7

The long noncoding RNA HOTAIR has tissue and cell type-dependent effects on HOX gene expression and phenotype of urothelial cancer cells.

Heubach J, Monsior J, Deenen R, Niegisch G, Szarvas T, Niedworok C, Schulz WA, Hoffmann MJ. Heubach J, et al. Among authors: niegisch g. Mol Cancer. 2015 May 21;14:108. doi: 10.1186/s12943-015-0371-8. Mol Cancer. 2015. PMID: 25994132 Free PMC article.

8

Inhibition of Class I Histone Deacetylases 1 and 2 Promotes Urothelial Carcinoma Cell Death by Various Mechanisms.

Pinkerneil M, Hoffmann MJ, Deenen R, Köhrer K, Arent T, Schulz WA, Niegisch G. Pinkerneil M, et al. Among authors: niegisch g. Mol Cancer Ther. 2016 Feb;15(2):299-312. doi: 10.1158/1535-7163.MCT-15-0618. Epub 2016 Jan 15. Mol Cancer Ther. 2016. PMID: 26772204

9

Distinct mechanisms contribute to acquired cisplatin resistance of urothelial carcinoma cells.

Höhn A, Krüger K, Skowron MA, Bormann S, Schumacher L, Schulz WA, Hoffmann MJ, Niegisch G, Fritz G. Höhn A, et al. Among authors: niegisch g. Oncotarget. 2016 Jul 5;7(27):41320-41335. doi: 10.18632/oncotarget.9321. Oncotarget. 2016. PMID: 27191498 Free PMC article.

10

Evaluation of the Therapeutic Potential of the Novel Isotype Specific HDAC Inhibitor 4SC-202 in Urothelial Carcinoma Cell Lines.

Pinkerneil M, Hoffmann MJ, Kohlhof H, Schulz WA, Niegisch G. Pinkerneil M, et al. Among authors: niegisch g. Target Oncol. 2016 Dec;11(6):783-798. doi: 10.1007/s11523-016-0444-7. Target Oncol. 2016. PMID: 27250763 Free PMC article.

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