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Effects of Spironolactone and Chlorthalidone on Cardiovascular Structure and Function in Chronic Kidney Disease: A Randomized, Open-Label Trial.
Edwards NC, Price AM, Mehta S, Hiemstra TF, Kaur A, Greasley PJ, Webb DJ, Dhaun N, MacIntyre IM, Farrah T, Melville V, Herrey AS, Slinn G, Wale R, Ives N, Wheeler DC, Wilkinson I, Steeds RP, Ferro CJ, Townend JN. Edwards NC, et al. Among authors: melville v. Clin J Am Soc Nephrol. 2021 Oct;16(10):1491-1501. doi: 10.2215/CJN.01930221. Epub 2021 Aug 30. Clin J Am Soc Nephrol. 2021. PMID: 34462286 Free PMC article. Clinical Trial.
Blood pressure and not uraemia is the major determinant of arterial stiffness and endothelial dysfunction in patients with chronic kidney disease and minimal co-morbidity.
Lilitkarntakul P, Dhaun N, Melville V, Blackwell S, Talwar DK, Liebman B, Asai T, Pollock J, Goddard J, Webb DJ. Lilitkarntakul P, et al. Among authors: melville v. Atherosclerosis. 2011 May;216(1):217-25. doi: 10.1016/j.atherosclerosis.2011.01.045. Epub 2011 Mar 3. Atherosclerosis. 2011. PMID: 21376323
32 results