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Targeted T cell receptor gene editing provides predictable T cell product function for immunotherapy.
Müller TR, Jarosch S, Hammel M, Leube J, Grassmann S, Bernard B, Effenberger M, Andrä I, Chaudhry MZ, Käuferle T, Malo A, Cicin-Sain L, Steinberger P, Feuchtinger T, Protzer U, Schumann K, Neuenhahn M, Schober K, Busch DH. Müller TR, et al. Among authors: protzer u. Cell Rep Med. 2021 Aug 17;2(8):100374. doi: 10.1016/j.xcrm.2021.100374. eCollection 2021 Aug 17. Cell Rep Med. 2021. PMID: 34467251 Free PMC article.
Overnight resting of PBMC changes functional signatures of antigen specific T- cell responses: impact for immune monitoring within clinical trials.
Kutscher S, Dembek CJ, Deckert S, Russo C, Körber N, Bogner JR, Geisler F, Umgelter A, Neuenhahn M, Albrecht J, Cosma A, Protzer U, Bauer T. Kutscher S, et al. Among authors: protzer u. PLoS One. 2013 Oct 11;8(10):e76215. doi: 10.1371/journal.pone.0076215. eCollection 2013. PLoS One. 2013. PMID: 24146841 Free PMC article.
T Cells Engineered to Express a T-Cell Receptor Specific for Glypican-3 to Recognize and Kill Hepatoma Cells In Vitro and in Mice.
Dargel C, Bassani-Sternberg M, Hasreiter J, Zani F, Bockmann JH, Thiele F, Bohne F, Wisskirchen K, Wilde S, Sprinzl MF, Schendel DJ, Krackhardt AM, Uckert W, Wohlleber D, Schiemann M, Stemmer K, Heikenwälder M, Busch DH, Richter G, Mann M, Protzer U. Dargel C, et al. Among authors: protzer u. Gastroenterology. 2015 Oct;149(4):1042-52. doi: 10.1053/j.gastro.2015.05.055. Epub 2015 Jun 5. Gastroenterology. 2015. PMID: 26052074
Isolation and functional characterization of hepatitis B virus-specific T-cell receptors as new tools for experimental and clinical use.
Wisskirchen K, Metzger K, Schreiber S, Asen T, Weigand L, Dargel C, Witter K, Kieback E, Sprinzl MF, Uckert W, Schiemann M, Busch DH, Krackhardt AM, Protzer U. Wisskirchen K, et al. Among authors: protzer u. PLoS One. 2017 Aug 8;12(8):e0182936. doi: 10.1371/journal.pone.0182936. eCollection 2017. PLoS One. 2017. PMID: 28792537 Free PMC article.
T cell receptor grafting allows virological control of Hepatitis B virus infection.
Wisskirchen K, Kah J, Malo A, Asen T, Volz T, Allweiss L, Wettengel JM, Lütgehetmann M, Urban S, Bauer T, Dandri M, Protzer U. Wisskirchen K, et al. Among authors: protzer u. J Clin Invest. 2019 Apr 30;129(7):2932-2945. doi: 10.1172/JCI120228. J Clin Invest. 2019. PMID: 31039136 Free PMC article.
340 results