Dong M - Search Results

1

Ebselen Not Only Inhibits Clostridioides difficile Toxins but Displays Redox-Associated Cellular Killing.

Marreddy RKR, Olaitan AO, May JN, Dong M, Hurdle JG. Marreddy RKR, et al. Among authors: dong m. Microbiol Spectr. 2021 Oct 31;9(2):e0044821. doi: 10.1128/Spectrum.00448-21. Epub 2021 Sep 1. Microbiol Spectr. 2021. PMID: 34468187 Free PMC article.

2

Frizzled proteins are colonic epithelial receptors for C. difficile toxin B.

Tao L, Zhang J, Meraner P, Tovaglieri A, Wu X, Gerhard R, Zhang X, Stallcup WB, Miao J, He X, Hurdle JG, Breault DT, Brass AL, Dong M. Tao L, et al. Among authors: dong m. Nature. 2016 Oct 20;538(7625):350-355. doi: 10.1038/nature19799. Epub 2016 Sep 28. Nature. 2016. PMID: 27680706 Free PMC article.

3

Phylogenomics of 8,839 Clostridioides difficile genomes reveals recombination-driven evolution and diversification of toxin A and B.

Mansfield MJ, Tremblay BJ, Zeng J, Wei X, Hodgins H, Worley J, Bry L, Dong M, Doxey AC. Mansfield MJ, et al. Among authors: dong m. PLoS Pathog. 2020 Dec 28;16(12):e1009181. doi: 10.1371/journal.ppat.1009181. eCollection 2020 Dec. PLoS Pathog. 2020. PMID: 33370413 Free PMC article.

4

Functional analyses of epidemic Clostridioides difficile toxin B variants reveal their divergence in utilizing receptors and inducing pathology.

Pan Z, Zhang Y, Luo J, Li D, Zhou Y, He L, Yang Q, Dong M, Tao L. Pan Z, et al. Among authors: dong m. PLoS Pathog. 2021 Jan 28;17(1):e1009197. doi: 10.1371/journal.ppat.1009197. eCollection 2021 Jan. PLoS Pathog. 2021. PMID: 33507919 Free PMC article.

5

Structural basis for CSPG4 as a receptor for TcdB and a therapeutic target in Clostridioides difficile infection.

Chen P, Zeng J, Liu Z, Thaker H, Wang S, Tian S, Zhang J, Tao L, Gutierrez CB, Xing L, Gerhard R, Huang L, Dong M, Jin R. Chen P, et al. Among authors: dong m. Nat Commun. 2021 Jun 18;12(1):3748. doi: 10.1038/s41467-021-23878-3. Nat Commun. 2021. PMID: 34145250 Free PMC article.

6

Structure and conformational dynamics of Clostridioides difficile toxin A.

Chen B, Basak S, Chen P, Zhang C, Perry K, Tian S, Yu C, Dong M, Huang L, Bowen ME, Jin R. Chen B, et al. Among authors: dong m. Life Sci Alliance. 2022 Mar 15;5(6):e202201383. doi: 10.26508/lsa.202201383. Print 2022 Jun. Life Sci Alliance. 2022. PMID: 35292538 Free PMC article.

7

Clostridioides difficile spore: coat assembly and formation.

Zeng J, Wang H, Dong M, Tian GB. Zeng J, et al. Among authors: dong m. Emerg Microbes Infect. 2022 Dec;11(1):2340-2349. doi: 10.1080/22221751.2022.2119168. Emerg Microbes Infect. 2022. PMID: 36032037 Free PMC article. Review.

8

C. difficile intoxicates neurons and pericytes to drive neurogenic inflammation.

Manion J, Musser MA, Kuziel GA, Liu M, Shepherd A, Wang S, Lee PG, Zhao L, Zhang J, Marreddy RKR, Goldsmith JD, Yuan K, Hurdle JG, Gerhard R, Jin R, Rakoff-Nahoum S, Rao M, Dong M. Manion J, et al. Among authors: dong m. Nature. 2023 Oct;622(7983):611-618. doi: 10.1038/s41586-023-06607-2. Epub 2023 Sep 12. Nature. 2023. PMID: 37699522 Free PMC article.

9

Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B.

Chen P, Tao L, Wang T, Zhang J, He A, Lam KH, Liu Z, He X, Perry K, Dong M, Jin R. Chen P, et al. Among authors: dong m. Science. 2018 May 11;360(6389):664-669. doi: 10.1126/science.aar1999. Science. 2018. PMID: 29748286 Free PMC article.

10

Structural insight into Wnt signaling inhibition by Clostridium difficile toxin B.

Chen P, Tao L, Liu Z, Dong M, Jin R. Chen P, et al. Among authors: dong m. FEBS J. 2019 Mar;286(5):874-881. doi: 10.1111/febs.14681. Epub 2018 Nov 1. FEBS J. 2019. PMID: 30347517 Free PMC article. Review.

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