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A Novel Single Cell RNA-seq Analysis of Non-Myeloid Circulating Cells in Late Sepsis.
Darden DB, Dong X, Brusko MA, Kelly L, Fenner B, Rincon JC, Dirain ML, Ungaro R, Nacionales DC, Gauthier M, Kladde M, Brusko TM, Bihorac A, Moore FA, Loftus T, Bacher R, Moldawer LL, Mohr AM, Efron PA. Darden DB, et al. Among authors: moore fa. Front Immunol. 2021 Aug 16;12:696536. doi: 10.3389/fimmu.2021.696536. eCollection 2021. Front Immunol. 2021. PMID: 34484194 Free PMC article.
Aged mice are unable to mount an effective myeloid response to sepsis.
Nacionales DC, Gentile LF, Vanzant E, Lopez MC, Cuenca A, Cuenca AG, Ungaro R, Li Y, Baslanti TO, Bihorac A, Moore FA, Baker HV, Leeuwenburgh C, Moldawer LL, Efron PA. Nacionales DC, et al. Among authors: moore fa. J Immunol. 2014 Jan 15;192(2):612-22. doi: 10.4049/jimmunol.1302109. Epub 2013 Dec 13. J Immunol. 2014. PMID: 24337739 Free PMC article.
Protective immunity and defects in the neonatal and elderly immune response to sepsis.
Gentile LF, Nacionales DC, Lopez MC, Vanzant E, Cuenca A, Cuenca AG, Ungaro R, Szpila BE, Larson S, Joseph A, Moore FA, Leeuwenburgh C, Baker HV, Moldawer LL, Efron PA. Gentile LF, et al. Among authors: moore fa. J Immunol. 2014 Apr 1;192(7):3156-65. doi: 10.4049/jimmunol.1301726. Epub 2014 Mar 3. J Immunol. 2014. PMID: 24591376 Free PMC article.
Innate Immunity in the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome and Its Implications for Therapy.
Horiguchi H, Loftus TJ, Hawkins RB, Raymond SL, Stortz JA, Hollen MK, Weiss BP, Miller ES, Bihorac A, Larson SD, Mohr AM, Brakenridge SC, Tsujimoto H, Ueno H, Moore FA, Moldawer LL, Efron PA; Sepsis and Critical Illness Research Center Investigators. Horiguchi H, et al. Among authors: moore fa. Front Immunol. 2018 Apr 4;9:595. doi: 10.3389/fimmu.2018.00595. eCollection 2018. Front Immunol. 2018. PMID: 29670613 Free PMC article. Review.
Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis.
Hollen MK, Stortz JA, Darden D, Dirain ML, Nacionales DC, Hawkins RB, Cox MC, Lopez MC, Rincon JC, Ungaro R, Wang Z, Wu Q, Brumback B, Gauthier ML, Kladde M, Leeuwenburgh C, Segal M, Bihorac A, Brakenridge S, Moore FA, Baker HV, Mohr AM, Moldawer LL, Efron PA. Hollen MK, et al. Among authors: moore fa. Crit Care. 2019 Nov 13;23(1):355. doi: 10.1186/s13054-019-2628-x. Crit Care. 2019. PMID: 31722736 Free PMC article.
Single-Cell RNA-seq of Human Myeloid-Derived Suppressor Cells in Late Sepsis Reveals Multiple Subsets With Unique Transcriptional Responses: A Pilot Study.
Darden DB, Bacher R, Brusko MA, Knight P, Hawkins RB, Cox MC, Dirain ML, Ungaro R, Nacionales DC, Rincon JC, Gauthier ML, Kladde M, Bihorac A, Brusko TM, Moore FA, Brakenridge SC, Mohr AM, Moldawer LL, Efron PA. Darden DB, et al. Among authors: moore fa. Shock. 2021 May 1;55(5):587-595. doi: 10.1097/SHK.0000000000001671. Shock. 2021. PMID: 33021571 Free PMC article.
Transcriptomic responses from improved murine sepsis models can better mimic human surgical sepsis.
Efron PA, Darden DB, Wang Z, Nacionales DC, Lopez MC, Hawkins RB, Cox MC, Rincon JC, Ungaro R, Dirain ML, Ghita GL, Chen T, Billiar TR, Delano MJ, Leeuwenburgh C, Bihorac A, Brakenridge SC, Moore FA, Mohr AM, Tompkins RG, Brumback BA, Baker HV, Upchurch GR, Moldawer LL. Efron PA, et al. Among authors: moore fa. FASEB J. 2021 Feb;35(2):e21156. doi: 10.1096/fj.202002150R. Epub 2020 Nov 2. FASEB J. 2021. PMID: 33140449 Free PMC article.
Immunological Endotyping of Chronic Critical Illness After Severe Sepsis.
Fenner BP, Darden DB, Kelly LS, Rincon J, Brakenridge SC, Larson SD, Moore FA, Efron PA, Moldawer LL. Fenner BP, et al. Among authors: moore fa. Front Med (Lausanne). 2021 Feb 15;7:616694. doi: 10.3389/fmed.2020.616694. eCollection 2020. Front Med (Lausanne). 2021. PMID: 33659259 Free PMC article. Review.
Persistent inflammation, immunosuppression, and catabolism syndrome after severe blunt trauma.
Vanzant EL, Lopez CM, Ozrazgat-Baslanti T, Ungaro R, Davis R, Cuenca AG, Gentile LF, Nacionales DC, Cuenca AL, Bihorac A, Leeuwenburgh C, Lanz J, Baker HV, McKinley B, Moldawer LL, Moore FA, Efron PA. Vanzant EL, et al. Among authors: moore fa. J Trauma Acute Care Surg. 2014 Jan;76(1):21-9; discussion 29-30. doi: 10.1097/TA.0b013e3182ab1ab5. J Trauma Acute Care Surg. 2014. PMID: 24368353 Free PMC article.
502 results