Lee K - Search Results

1

Scaffold Repurposing of In-House Small Molecule Candidates Leads to Discovery of First-in-Class CDK-1/HER-2 Dual Inhibitors: In Vitro and In Silico Screening.

Elkamhawy A, Ammar UM, Paik S, Abdellattif MH, Elsherbeny MH, Lee K, Roh EJ. Elkamhawy A, et al. Among authors: lee k. Molecules. 2021 Sep 1;26(17):5324. doi: 10.3390/molecules26175324. Molecules. 2021. PMID: 34500757 Free PMC article.

2

Suppression of Hepatitis C Virus Genome Replication and Particle Production by a Novel Diacylglycerol Acyltransferases Inhibitor.

Kim D, Goo JI, Kim MI, Lee SJ, Choi M, Than TT, Nguyen PH, Windisch MP, Lee K, Choi Y, Lee C. Kim D, et al. Among authors: lee sj, lee k, lee c. Molecules. 2018 Aug 20;23(8):2083. doi: 10.3390/molecules23082083. Molecules. 2018. PMID: 30127285 Free PMC article.

3

An Overview of Saturated Cyclic Ethers: Biological Profiles and Synthetic Strategies.

Lu Q, Harmalkar DS, Choi Y, Lee K. Lu Q, et al. Among authors: lee k. Molecules. 2019 Oct 21;24(20):3778. doi: 10.3390/molecules24203778. Molecules. 2019. PMID: 31640154 Free PMC article. Review.

4

Sulfonamide-based 4-anilinoquinoline derivatives as novel dual Aurora kinase (AURKA/B) inhibitors: Synthesis, biological evaluation and in silico insights.

Al-Sanea MM, Elkamhawy A, Paik S, Lee K, El Kerdawy AM, Syed Nasir Abbas B, Joo Roh E, Eldehna WM, Elshemy HAH, Bakr RB, Ali Farahat I, Alzarea AI, Alzarea SI, Alharbi KS, Abdelgawad MA. Al-Sanea MM, et al. Among authors: lee k. Bioorg Med Chem. 2020 Jul 1;28(13):115525. doi: 10.1016/j.bmc.2020.115525. Epub 2020 Apr 25. Bioorg Med Chem. 2020. PMID: 32371117

5

Discovery of N-(1-(3-fluorobenzoyl)-1H-indol-5-yl)pyrazine-2-carboxamide: a novel, selective, and competitive indole-based lead inhibitor for human monoamine oxidase B.

Elkamhawy A, Paik S, Kim HJ, Park JH, Londhe AM, Lee K, Pae AN, Park KD, Roh EJ. Elkamhawy A, et al. Among authors: lee k. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1568-1580. doi: 10.1080/14756366.2020.1800666. J Enzyme Inhib Med Chem. 2020. PMID: 32752896 Free PMC article.

6

Structure Activity Relationship of Key Heterocyclic Anti-Angiogenic Leads of Promising Potential in the Fight against Cancer.

Nada H, Elkamhawy A, Lee K. Nada H, et al. Among authors: lee k. Molecules. 2021 Jan 21;26(3):553. doi: 10.3390/molecules26030553. Molecules. 2021. PMID: 33494492 Free PMC article. Review.

7

Pharmacokinetic Characterization of LW6, a Novel Hypoxia-Inducible Factor-1α (HIF-1α) Inhibitor in Mice.

Lee JY, Lee K, Lee K, Kang JS, Kim MJ, Yoo DG, Kim JA, Shin EJ, Oh SJ. Lee JY, et al. Among authors: lee k. Molecules. 2021 Apr 12;26(8):2226. doi: 10.3390/molecules26082226. Molecules. 2021. PMID: 33921487 Free PMC article.

8

The Journey of DDR1 and DDR2 Kinase Inhibitors as Rising Stars in the Fight Against Cancer.

Elkamhawy A, Lu Q, Nada H, Woo J, Quan G, Lee K. Elkamhawy A, et al. Among authors: lee k. Int J Mol Sci. 2021 Jun 18;22(12):6535. doi: 10.3390/ijms22126535. Int J Mol Sci. 2021. PMID: 34207360 Free PMC article. Review.

9

New horizons in drug discovery of lymphocyte-specific protein tyrosine kinase (Lck) inhibitors: a decade review (2011-2021) focussing on structure-activity relationship (SAR) and docking insights.

Elkamhawy A, Ali EMH, Lee K. Elkamhawy A, et al. Among authors: lee k. J Enzyme Inhib Med Chem. 2021 Dec;36(1):1574-1602. doi: 10.1080/14756366.2021.1937143. J Enzyme Inhib Med Chem. 2021. PMID: 34233563 Free PMC article. Review.

10

Discovery of novel and potent safinamide-based derivatives as highly selective hMAO-B inhibitors for treatment of Parkinson's disease (PD): Design, synthesis, in vitro, in vivo and in silico biological studies.

Elkamhawy A, Paik S, Park JH, Kim HJ, Hassan AHE, Lee K, Park KD, Roh EJ. Elkamhawy A, et al. Among authors: lee k. Bioorg Chem. 2021 Oct;115:105233. doi: 10.1016/j.bioorg.2021.105233. Epub 2021 Aug 2. Bioorg Chem. 2021. PMID: 34390968

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