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Page 1
Chromatin-based, in cis and in trans regulatory rewiring underpins distinct oncogenic transcriptomes in multiple myeloma.
Alvarez-Benayas J, Trasanidis N, Katsarou A, Ponnusamy K, Chaidos A, May PC, Xiao X, Bua M, Atta M, Roberts IAG, Auner HW, Hatjiharissi E, Papaioannou M, Caputo VS, Sudbery IM, Karadimitris A. Alvarez-Benayas J, et al. Among authors: trasanidis n. Nat Commun. 2021 Sep 14;12(1):5450. doi: 10.1038/s41467-021-25704-2. Nat Commun. 2021. PMID: 34521827 Free PMC article.
The innate sensor ZBP1-IRF3 axis regulates cell proliferation in multiple myeloma.
Ponnusamy K, Tzioni MM, Begum M, Robinson ME, Caputo VS, Katsarou A, Trasanidis N, Xiao X, Kostopoulos IV, Iskander D, Roberts I, Trivedi P, Auner HW, Naresh K, Chaidos A, Karadimitris A. Ponnusamy K, et al. Among authors: trasanidis n. Haematologica. 2022 Mar 1;107(3):721-732. doi: 10.3324/haematol.2020.274480. Haematologica. 2022. PMID: 33596642 Free PMC article.
Systems medicine dissection of chr1q-amp reveals a novel PBX1-FOXM1 axis for targeted therapy in multiple myeloma.
Trasanidis N, Katsarou A, Ponnusamy K, Shen YA, Kostopoulos IV, Bergonia B, Keren K, Reema P, Xiao X, Szydlo RM, Sabbattini PMR, Roberts IAG, Auner HW, Naresh KN, Chaidos A, Wang TL, Magnani L, Caputo VS, Karadimitris A. Trasanidis N, et al. Blood. 2022 Mar 31;139(13):1939-1953. doi: 10.1182/blood.2021014391. Blood. 2022. PMID: 35015835 Free article.
Single-cell profiling of human bone marrow progenitors reveals mechanisms of failing erythropoiesis in Diamond-Blackfan anemia.
Iskander D, Wang G, Heuston EF, Christodoulidou C, Psaila B, Ponnusamy K, Ren H, Mokhtari Z, Robinson M, Chaidos A, Trivedi P, Trasanidis N, Katsarou A, Szydlo R, Palii CG, Zaidi MH, Al-Oqaily Q, Caputo VS, Roy A, Harrington Y, Karnik L, Naresh K, Mead AJ, Thongjuea S, Brand M, de la Fuente J, Bodine DM, Roberts I, Karadimitris A. Iskander D, et al. Among authors: trasanidis n. Sci Transl Med. 2021 Sep 8;13(610):eabf0113. doi: 10.1126/scitranslmed.abf0113. Epub 2021 Sep 8. Sci Transl Med. 2021. PMID: 34516827
MAF functions as a pioneer transcription factor that initiates and sustains myelomagenesis.
Katsarou A, Trasanidis N, Ponnusamy K, Kostopoulos IV, Alvarez-Benayas J, Papaleonidopoulou F, Keren K, Sabbattini PMR, Feldhahn N, Papaioannou M, Hatjiharissi E, Sudbery IM, Chaidos A, Caputo VS, Karadimitris A. Katsarou A, et al. Among authors: trasanidis n. Blood Adv. 2023 Nov 14;7(21):6395-6410. doi: 10.1182/bloodadvances.2023009772. Blood Adv. 2023. PMID: 37224458 Free PMC article.