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Parity associates with chromosomal damage in uterine leiomyomas.
Kuisma H, Bramante S, Rajamäki K, Sipilä LJ, Kaasinen E, Kaukomaa J, Palin K, Mäkinen N, Sjöberg J, Sarvilinna N, Taipale J, Kauppi L, Tumiati M, Hassinen A, Pitkäniemi J, Jalkanen J, Heikkinen S, Pasanen A, Heikinheimo O, Bützow R, Välimäki N, Aaltonen LA. Kuisma H, et al. Among authors: sjoberg j. Nat Commun. 2021 Sep 14;12(1):5448. doi: 10.1038/s41467-021-25806-x. Nat Commun. 2021. PMID: 34521855 Free PMC article.
MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas.
Mäkinen N, Mehine M, Tolvanen J, Kaasinen E, Li Y, Lehtonen HJ, Gentile M, Yan J, Enge M, Taipale M, Aavikko M, Katainen R, Virolainen E, Böhling T, Koski TA, Launonen V, Sjöberg J, Taipale J, Vahteristo P, Aaltonen LA. Mäkinen N, et al. Among authors: sjoberg j. Science. 2011 Oct 14;334(6053):252-5. doi: 10.1126/science.1208930. Epub 2011 Aug 25. Science. 2011. PMID: 21868628
Characterization of uterine leiomyomas by whole-genome sequencing.
Mehine M, Kaasinen E, Mäkinen N, Katainen R, Kämpjärvi K, Pitkänen E, Heinonen HR, Bützow R, Kilpivaara O, Kuosmanen A, Ristolainen H, Gentile M, Sjöberg J, Vahteristo P, Aaltonen LA. Mehine M, et al. Among authors: sjoberg j. N Engl J Med. 2013 Jul 4;369(1):43-53. doi: 10.1056/NEJMoa1302736. Epub 2013 Jun 5. N Engl J Med. 2013. PMID: 23738515 Free article.
MED12 mutation frequency in unselected sporadic uterine leiomyomas.
Heinonen HR, Sarvilinna NS, Sjöberg J, Kämpjärvi K, Pitkänen E, Vahteristo P, Mäkinen N, Aaltonen LA. Heinonen HR, et al. Among authors: sjoberg j. Fertil Steril. 2014 Oct;102(4):1137-42. doi: 10.1016/j.fertnstert.2014.06.040. Epub 2014 Aug 6. Fertil Steril. 2014. PMID: 25108465 Free article.
Integrated data analysis reveals uterine leiomyoma subtypes with distinct driver pathways and biomarkers.
Mehine M, Kaasinen E, Heinonen HR, Mäkinen N, Kämpjärvi K, Sarvilinna N, Aavikko M, Vähärautio A, Pasanen A, Bützow R, Heikinheimo O, Sjöberg J, Pitkänen E, Vahteristo P, Aaltonen LA. Mehine M, et al. Among authors: sjoberg j. Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1315-20. doi: 10.1073/pnas.1518752113. Epub 2016 Jan 19. Proc Natl Acad Sci U S A. 2016. PMID: 26787895 Free PMC article.
171 results