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Page 1
Resident memory CD8+ T cells in regional lymph nodes mediate immunity to metastatic melanoma.
Molodtsov AK, Khatwani N, Vella JL, Lewis KA, Zhao Y, Han J, Sullivan DE, Searles TG, Preiss NK, Shabaneh TB, Zhang P, Hawkes AR, Malik BT, Kolling FW 4th, Usherwood EJ, Wong SL, Phillips JD, Shirai K, Angeles CV, Yan S, Curiel TJ, Huang YH, Cheng C, Turk MJ. Molodtsov AK, et al. Among authors: searles tg. Immunity. 2021 Sep 14;54(9):2117-2132.e7. doi: 10.1016/j.immuni.2021.08.019. Immunity. 2021. PMID: 34525340 Free PMC article.
Memory CD8+ T cell responses to cancer.
Han J, Khatwani N, Searles TG, Turk MJ, Angeles CV. Han J, et al. Among authors: searles tg. Semin Immunol. 2020 Jun;49:101435. doi: 10.1016/j.smim.2020.101435. Epub 2020 Nov 30. Semin Immunol. 2020. PMID: 33272898 Free PMC article. Review.
The Effect of Lung Resection for NSCLC on Circulating Immune Cells: A Pilot Study.
Phillips JD, Fay KA, Bergeron AJ, Zhang P, Mielcarz DW, Calkins AM, Searles TG, Christensen BC, Finley DJ, Turk MJ, Channon JY. Phillips JD, et al. Among authors: searles tg. Curr Oncol. 2023 May 17;30(5):5116-5134. doi: 10.3390/curroncol30050387. Curr Oncol. 2023. PMID: 37232845 Free PMC article.
CD39 is expressed on functional effector and tissue resident memory CD8+ T cells.
Isaacs JF, Degefu HN, Chen T, Kleist SA, Musial SC, Ford MA, Searles TG, Lin CC, Skorput AGJ, Shirai K, Turk MJ, Zanazzi GJ, Rosato PC. Isaacs JF, et al. Among authors: searles tg. bioRxiv [Preprint]. 2024 Mar 17:2024.03.15.585252. doi: 10.1101/2024.03.15.585252. bioRxiv. 2024. Update in: J Immunol. 2024 Sep 1;213(5):588-599. doi: 10.4049/jimmunol.2400151. PMID: 38559200 Free PMC article. Updated. Preprint.
Validation of Ligand Tetramers for the Detection of Antigen-Specific Lymphocytes.
Fitzpatrick KS, Degefu HN, Poljakov K, Bibby MG, Remington AJ, Searles TG, Gray MD, Boonyaratanakornkit J, Rosato PC, Taylor JJ. Fitzpatrick KS, et al. Among authors: searles tg. J Immunol. 2023 Apr 15;210(8):1156-1165. doi: 10.4049/jimmunol.2200934. J Immunol. 2023. PMID: 36883850 Free PMC article.
Depletion of conventional CD4+ T cells is required for robust priming and dissemination of tumor antigen-specific CD8+ T cells in the setting of anti-CD4 therapy.
Ramirez DE, Dragnev CPC, Searles TG, Spicer N, Chen T, Lines JL, Hawkes AR, Davis WL, Mohamed A, Shirai K, Phillips JD, Rosato PC, Huang YH, Turk MJ. Ramirez DE, et al. Among authors: searles tg. J Immunother Cancer. 2024 Nov 9;12(11):e010170. doi: 10.1136/jitc-2024-010170. J Immunother Cancer. 2024. PMID: 39521617 Free PMC article.