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Cardioprotecive Properties of Known Agents in Rat Ischemia-Reperfusion Model Under Clinically Relevant Conditions: Only the NAD Precursor Nicotinamide Riboside Reduces Infarct Size in Presence of Fentanyl, Midazolam and Cangrelor, but Not Propofol.
Xiao Y, Phelp P, Wang Q, Bakker D, Nederlof R, Hollmann MW, Zuurbier CJ. Xiao Y, et al. Among authors: nederlof r. Front Cardiovasc Med. 2021 Aug 30;8:712478. doi: 10.3389/fcvm.2021.712478. eCollection 2021. Front Cardiovasc Med. 2021. PMID: 34527711 Free PMC article.
The Redox Modulating Sonlicromanol Active Metabolite KH176m and the Antioxidant MPG Protect Against Short-Duration Cardiac Ischemia-Reperfusion Injury.
Xiao Y, Yim K, Zhang H, Bakker D, Nederlof R, Smeitink JAM, Renkema H, Hollmann MW, Weber NC, Zuurbier CJ. Xiao Y, et al. Among authors: nederlof r. Cardiovasc Drugs Ther. 2021 Aug;35(4):745-758. doi: 10.1007/s10557-021-07189-9. Epub 2021 Apr 29. Cardiovasc Drugs Ther. 2021. PMID: 33914182 Free PMC article.
Reduced hexokinase II impairs muscle function 2 wk after ischemia-reperfusion through increased cell necrosis and fibrosis.
Smeele KM, Eerbeek O, Schaart G, Koeman A, Bezemer R, Nelson JK, Ince C, Nederlof R, Boek M, Laakso M, de Haan A, Drost MR, Hollmann MW, Zuurbier CJ. Smeele KM, et al. Among authors: nederlof r. J Appl Physiol (1985). 2012 Aug 15;113(4):608-18. doi: 10.1152/japplphysiol.01494.2011. Epub 2012 Jun 21. J Appl Physiol (1985). 2012. PMID: 22723631 Free article.
Reducing mitochondrial bound hexokinase II mediates transition from non-injurious into injurious ischemia/reperfusion of the intact heart.
Nederlof R, Gürel-Gurevin E, Eerbeek O, Xie C, Deijs GS, Konkel M, Hu J, Weber NC, Schumacher CA, Baartscheer A, Mik EG, Hollmann MW, Akar FG, Zuurbier CJ. Nederlof R, et al. J Physiol Biochem. 2016 Aug;73(3):323-333. doi: 10.1007/s13105-017-0555-3. Epub 2017 Mar 3. J Physiol Biochem. 2016. PMID: 28258543 Free PMC article.
30 results