Kashimoto S - Search Results

1

Discovery of AS-1763: A Potent, Selective, Noncovalent, and Orally Available Inhibitor of Bruton's Tyrosine Kinase.

Kawahata W, Asami T, Kiyoi T, Irie T, Kashimoto S, Furuichi H, Sawa M. Kawahata W, et al. Among authors: kashimoto s. J Med Chem. 2021 Oct 14;64(19):14129-14141. doi: 10.1021/acs.jmedchem.1c01279. Epub 2021 Sep 16. J Med Chem. 2021. PMID: 34529443

2

TNIK inhibition abrogates colorectal cancer stemness.

Masuda M, Uno Y, Ohbayashi N, Ohata H, Mimata A, Kukimoto-Niino M, Moriyama H, Kashimoto S, Inoue T, Goto N, Okamoto K, Shirouzu M, Sawa M, Yamada T. Masuda M, et al. Among authors: kashimoto s. Nat Commun. 2016 Aug 26;7:12586. doi: 10.1038/ncomms12586. Nat Commun. 2016. PMID: 27562646 Free PMC article.

3

Pharmacological blockage of transforming growth factor-β signalling by a Traf2- and Nck-interacting kinase inhibitor, NCB-0846.

Sugano T, Masuda M, Takeshita F, Motoi N, Hirozane T, Goto N, Kashimoto S, Uno Y, Moriyama H, Sawa M, Nagakawa Y, Tsuchida A, Seike M, Gemma A, Yamada T. Sugano T, et al. Among authors: kashimoto s. Br J Cancer. 2021 Jan;124(1):228-236. doi: 10.1038/s41416-020-01162-3. Epub 2020 Nov 27. Br J Cancer. 2021. PMID: 33244122 Free PMC article.

4

Water-soluble pleuromutilin derivative with excellent in vitro and in vivo antibacterial activity against gram-positive pathogens.

Hirokawa Y, Kinoshita H, Tanaka T, Nakata K, Kitadai N, Fujimoto K, Kashimoto S, Kojima T, Kato S. Hirokawa Y, et al. Among authors: kashimoto s. J Med Chem. 2008 Apr 10;51(7):1991-4. doi: 10.1021/jm8000136. Epub 2008 Mar 11. J Med Chem. 2008. PMID: 18330977

5

Pleuromutilin derivatives having a purine ring. Part 1: new compounds with promising antibacterial activity against resistant Gram-positive pathogens.

Hirokawa Y, Kinoshita H, Tanaka T, Nakamura T, Fujimoto K, Kashimoto S, Kojima T, Kato S. Hirokawa Y, et al. Among authors: kashimoto s. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3556-61. doi: 10.1016/j.bmcl.2008.05.011. Epub 2008 May 4. Bioorg Med Chem Lett. 2008. PMID: 18511280

6

Recombinant human tumor necrosis factor--II. Antitumor effect on murine and human tumors transplanted in mice.

Sohmura Y, Nakata K, Yoshida H, Kashimoto S, Matsui Y, Furuichi H. Sohmura Y, et al. Among authors: kashimoto s. Int J Immunopharmacol. 1986;8(3):357-68. doi: 10.1016/0192-0561(86)90118-9. Int J Immunopharmacol. 1986. PMID: 3525434

7

Synthesis and structure-activity relationships of novel 7-substituted 1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acids as antitumor agents. Part 1.

Tomita K, Tsuzuki Y, Shibamori K, Tashima M, Kajikawa F, Sato Y, Kashimoto S, Chiba K, Hino K. Tomita K, et al. Among authors: kashimoto s. J Med Chem. 2002 Dec 5;45(25):5564-75. doi: 10.1021/jm010057b. J Med Chem. 2002. PMID: 12459024

8

Synthesis and structure-activity relationships of novel 7-substituted 1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acids as antitumor agents. Part 2.

Tsuzuki Y, Tomita K, Shibamori K, Sato Y, Kashimoto S, Chiba K. Tsuzuki Y, et al. Among authors: kashimoto s. J Med Chem. 2004 Apr 8;47(8):2097-109. doi: 10.1021/jm0304966. J Med Chem. 2004. PMID: 15056007

9

Pleuromutilin derivatives having a purine ring. Part 2: influence of the central spacer on the antibacterial activity against Gram-positive pathogens.

Hirokawa Y, Kinoshita H, Tanaka T, Nakamura T, Fujimoto K, Kashimoto S, Kojima T, Kato S. Hirokawa Y, et al. Among authors: kashimoto s. Bioorg Med Chem Lett. 2009 Jan 1;19(1):170-4. doi: 10.1016/j.bmcl.2008.10.123. Epub 2008 Nov 5. Bioorg Med Chem Lett. 2009. PMID: 19028096

10

Pleuromutilin derivatives having a purine ring. Part 3: synthesis and antibacterial activity of novel compounds possessing a piperazine ring spacer.

Hirokawa Y, Kinoshita H, Tanaka T, Nakamura T, Fujimoto K, Kashimoto S, Kojima T, Kato S. Hirokawa Y, et al. Among authors: kashimoto s. Bioorg Med Chem Lett. 2009 Jan 1;19(1):175-9. doi: 10.1016/j.bmcl.2008.10.127. Epub 2008 Nov 5. Bioorg Med Chem Lett. 2009. PMID: 19022668

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