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Differential requirement for the Polycomb repressor complex 2 in dendritic cell and tissue-resident myeloid cell homeostasis.
Zhan Y, Zhang Y, Zhang S, Coughlan H, Baldoni PL, Jacquelot N, Cao WHJ, Preston S, Louis C, Rautela J, Pellegrini M, Wicks IP, Alexander WS, Harrison LC, Lew AM, Smyth GK, Nutt SL, Chopin M. Zhan Y, et al. Among authors: coughlan h. Sci Immunol. 2021 Sep 17;6(63):eabf7268. doi: 10.1126/sciimmunol.abf7268. Epub 2021 Sep 17. Sci Immunol. 2021. PMID: 34533976
Transcription Factor PU.1 Promotes Conventional Dendritic Cell Identity and Function via Induction of Transcriptional Regulator DC-SCRIPT.
Chopin M, Lun AT, Zhan Y, Schreuder J, Coughlan H, D'Amico A, Mielke LA, Almeida FF, Kueh AJ, Dickins RA, Belz GT, Naik SH, Lew AM, Bouillet P, Herold MJ, Smyth GK, Corcoran LM, Nutt SL. Chopin M, et al. Among authors: coughlan h. Immunity. 2019 Jan 15;50(1):77-90.e5. doi: 10.1016/j.immuni.2018.11.010. Epub 2019 Jan 2. Immunity. 2019. PMID: 30611612 Free article.
An Erg-driven transcriptional program controls B cell lymphopoiesis.
Ng AP, Coughlan HD, Hediyeh-Zadeh S, Behrens K, Johanson TM, Low MSY, Bell CC, Gilan O, Chan YC, Kueh AJ, Boudier T, Feltham R, Gabrielyan A, DiRago L, Hyland CD, Ierino H, Mifsud S, Viney E, Willson T, Dawson MA, Allan RS, Herold MJ, Rogers K, Tarlinton DM, Smyth GK, Davis MJ, Nutt SL, Alexander WS. Ng AP, et al. Among authors: coughlan hd. Nat Commun. 2020 Jun 15;11(1):3013. doi: 10.1038/s41467-020-16828-y. Nat Commun. 2020. PMID: 32541654 Free PMC article.
Multi-level remodelling of chromatin underlying activation of human T cells.
Bediaga NG, Coughlan HD, Johanson TM, Garnham AL, Naselli G, Schröder J, Fearnley LG, Bandala-Sanchez E, Allan RS, Smyth GK, Harrison LC. Bediaga NG, et al. Sci Rep. 2021 Jan 12;11(1):528. doi: 10.1038/s41598-020-80165-9. Sci Rep. 2021. PMID: 33436846 Free PMC article.
Chromosomes distribute randomly to, but not within, human neutrophil nuclear lobes.
Keenan CR, Mlodzianoski MJ, Coughlan HD, Bediaga NG, Naselli G, Lucas EC, Wang Q, de Graaf CA, Hilton DJ, Harrison LC, Smyth GK, Rogers KL, Boudier T, Allan RS, Johanson TM. Keenan CR, et al. iScience. 2021 Feb 7;24(3):102161. doi: 10.1016/j.isci.2021.102161. eCollection 2021 Mar 19. iScience. 2021. PMID: 33665577 Free PMC article.
Type 1 conventional dendritic cell fate and function are controlled by DC-SCRIPT.
Zhang S, Coughlan HD, Ashayeripanah M, Seizova S, Kueh AJ, Brown DV, Cao W, Jacquelot N, D'Amico A, Lew AM, Zhan Y, Tonkin CJ, Villadangos JA, Smyth GK, Chopin M, Nutt SL. Zhang S, et al. Sci Immunol. 2021 Apr 2;6(58):eabf4432. doi: 10.1126/sciimmunol.abf4432. Sci Immunol. 2021. PMID: 33811060
56 results