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A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses.
Beumer J, Geurts MH, Lamers MM, Puschhof J, Zhang J, van der Vaart J, Mykytyn AZ, Breugem TI, Riesebosch S, Schipper D, van den Doel PB, de Lau W, Pleguezuelos-Manzano C, Busslinger G, Haagmans BL, Clevers H. Beumer J, et al. Among authors: haagmans bl. Nat Commun. 2021 Sep 17;12(1):5498. doi: 10.1038/s41467-021-25729-7. Nat Commun. 2021. PMID: 34535662 Free PMC article.
Coronaviruses and their therapy.
Haagmans BL, Osterhaus AD. Haagmans BL, et al. Antiviral Res. 2006 Sep;71(2-3):397-403. doi: 10.1016/j.antiviral.2006.05.019. Epub 2006 Jun 19. Antiviral Res. 2006. PMID: 16837072 Free PMC article. Review.
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC.
Raj VS, Mou H, Smits SL, Dekkers DH, Müller MA, Dijkman R, Muth D, Demmers JA, Zaki A, Fouchier RA, Thiel V, Drosten C, Rottier PJ, Osterhaus AD, Bosch BJ, Haagmans BL. Raj VS, et al. Among authors: haagmans bl. Nature. 2013 Mar 14;495(7440):251-4. doi: 10.1038/nature12005. Nature. 2013. PMID: 23486063 Free PMC article.
Isolation of MERS coronavirus from a dromedary camel, Qatar, 2014.
Raj VS, Farag EA, Reusken CB, Lamers MM, Pas SD, Voermans J, Smits SL, Osterhaus AD, Al-Mawlawi N, Al-Romaihi HE, AlHajri MM, El-Sayed AM, Mohran KA, Ghobashy H, Alhajri F, Al-Thani M, Al-Marri SA, El-Maghraby MM, Koopmans MP, Haagmans BL. Raj VS, et al. Among authors: haagmans bl. Emerg Infect Dis. 2014 Aug;20(8):1339-42. doi: 10.3201/eid2008.140663. Emerg Infect Dis. 2014. PMID: 25075761 Free PMC article.
Differential Expression of the Middle East Respiratory Syndrome Coronavirus Receptor in the Upper Respiratory Tracts of Humans and Dromedary Camels.
Widagdo W, Raj VS, Schipper D, Kolijn K, van Leenders GJLH, Bosch BJ, Bensaid A, Segalés J, Baumgärtner W, Osterhaus ADME, Koopmans MP, van den Brand JMA, Haagmans BL. Widagdo W, et al. Among authors: haagmans bl. J Virol. 2016 Apr 14;90(9):4838-4842. doi: 10.1128/JVI.02994-15. Print 2016 May. J Virol. 2016. PMID: 26889022 Free PMC article.
279 results