Wang J - Search Results

1

Drugs for the treatment of glaucoma: Targets, structure-activity relationships and clinical research.

Wu X, Yang X, Liang Q, Xue X, Huang J, Wang J, Xu Y, Tong R, Liu M, Zhou Q, Shi J. Wu X, et al. Among authors: wang j. Eur J Med Chem. 2021 Dec 15;226:113842. doi: 10.1016/j.ejmech.2021.113842. Epub 2021 Sep 11. Eur J Med Chem. 2021. PMID: 34536672 Review.

2

Recent progress on FAK inhibitors with dual targeting capabilities for cancer treatment.

Wu X, Wang J, Liang Q, Tong R, Huang J, Yang X, Xu Y, Wang W, Sun M, Shi J. Wu X, et al. Among authors: wang w, wang j. Biomed Pharmacother. 2022 Jul;151:113116. doi: 10.1016/j.biopha.2022.113116. Epub 2022 May 19. Biomed Pharmacother. 2022. PMID: 35598365 Free article. Review.

3

Recent Advances in Dual PI3K/mTOR Inhibitors for Tumour Treatment.

Wu X, Xu Y, Liang Q, Yang X, Huang J, Wang J, Zhang H, Shi J. Wu X, et al. Among authors: wang j. Front Pharmacol. 2022 May 9;13:875372. doi: 10.3389/fphar.2022.875372. eCollection 2022. Front Pharmacol. 2022. PMID: 35614940 Free PMC article. Review.

4

Design, synthesis, and Structure-Activity Relationships (SAR) of 3-vinylindazole derivatives as new selective tropomyosin receptor kinases (Trk) inhibitors.

Duan Y, Wang J, Zhu S, Tu ZC, Zhang Z, Chan S, Ding K. Duan Y, et al. Among authors: wang j. Eur J Med Chem. 2020 Oct 1;203:112552. doi: 10.1016/j.ejmech.2020.112552. Epub 2020 Jul 13. Eur J Med Chem. 2020. PMID: 32702585

5

Design, synthesis and biological evaluation of potent EGFR kinase inhibitors against 19D/T790M/C797S mutation.

Su Z, Yang T, Wang J, Lai M, Tong L, Wumaier G, Chen Z, Li S, Li H, Xie H, Zhao Z. Su Z, et al. Among authors: wang j. Bioorg Med Chem Lett. 2020 Aug 15;30(16):127327. doi: 10.1016/j.bmcl.2020.127327. Epub 2020 Jun 9. Bioorg Med Chem Lett. 2020. PMID: 32631532

6

An exploration of solvent-front region high affinity moiety leading to novel potent ALK & ROS1 dual inhibitors with mutant-combating effects.

Lei H, Jia F, Cao M, Wang J, Guo M, Zhu M, Zuo D, Zhai X. Lei H, et al. Among authors: wang j. Bioorg Med Chem. 2019 Oct 15;27(20):115051. doi: 10.1016/j.bmc.2019.115051. Epub 2019 Aug 21. Bioorg Med Chem. 2019. PMID: 31492532

7

Discovery of dihydro-β-agarofurans from Tripterygium wilfordii with their H₂O₂-induced SH-SY5Y cell protective effects.

Zhou L, He QJ, Hou ZL, Lu LW, Wang J, Huang XX, Lin B, Song SJ. Zhou L, et al. Among authors: wang j. Bioorg Chem. 2020 Nov;104:104247. doi: 10.1016/j.bioorg.2020.104247. Epub 2020 Sep 1. Bioorg Chem. 2020. PMID: 32911198

8

Enantiomeric neolignans from Picrasma quassioides exhibit distinctive cytotoxicity on hepatic carcinoma cells through ROS generation and apoptosis induction.

Lou LL, Yao GD, Wang J, Zhao WY, Wang XB, Huang XX, Song SJ. Lou LL, et al. Among authors: wang j, wang xb. Bioorg Med Chem Lett. 2018 May 1;28(8):1263-1268. doi: 10.1016/j.bmcl.2018.03.043. Epub 2018 Mar 17. Bioorg Med Chem Lett. 2018. PMID: 29567344

9

Approach in Improving Potency and Selectivity of Kinase Inhibitors: Allosteric Kinase Inhibitors.

Wei S, Zhao T, Wang J, Zhai X. Wei S, et al. Among authors: wang j. Mini Rev Med Chem. 2021;21(8):991-1003. doi: 10.2174/1389557521666201222144355. Mini Rev Med Chem. 2021. PMID: 33355051 Review.

10

Discovery of guaiane-type sesquiterpenoids from the roots of Daphne genkwa with neuroprotective effects.

Wang J, Liu QB, Hou ZL, Shi SC, Ren H, Yao GD, Lin B, Huang XX, Song SJ. Wang J, et al. Bioorg Chem. 2020 Jan;95:103545. doi: 10.1016/j.bioorg.2019.103545. Epub 2019 Dec 23. Bioorg Chem. 2020. PMID: 31927316

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