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Toward precision immunotherapy using multiplex immunohistochemistry and in silico methods to define the tumor immune microenvironment.
Widodo SS, Hutchinson RA, Fang Y, Mangiola S, Neeson PJ, Darcy PK, Barrow AD, Hovens CM, Dinevska M, Stylli SS, Mantamadiotis T. Widodo SS, et al. Among authors: mangiola s. Cancer Immunol Immunother. 2021 Jul;70(7):1811-1820. doi: 10.1007/s00262-020-02801-7. Epub 2021 Jan 3. Cancer Immunol Immunother. 2021. PMID: 33389014 Free PMC article. Review.
Prostate cancer cell-intrinsic interferon signaling regulates dormancy and metastatic outgrowth in bone.
Owen KL, Gearing LJ, Zanker DJ, Brockwell NK, Khoo WH, Roden DL, Cmero M, Mangiola S, Hong MK, Spurling AJ, McDonald M, Chan CL, Pasam A, Lyons RJ, Duivenvoorden HM, Ryan A, Butler LM, Mariadason JM, Giang Phan T, Hayes VM, Sandhu S, Swarbrick A, Corcoran NM, Hertzog PJ, Croucher PI, Hovens C, Parker BS. Owen KL, et al. Among authors: mangiola s. EMBO Rep. 2020 Jun 4;21(6):e50162. doi: 10.15252/embr.202050162. Epub 2020 Apr 21. EMBO Rep. 2020. PMID: 32314873 Free PMC article.
Combined BRAF, MEK, and CDK4/6 Inhibition Depletes Intratumoral Immune-Potentiating Myeloid Populations in Melanoma.
Lelliott EJ, Mangiola S, Ramsbottom KM, Zethoven M, Lim L, Lau PKH, Oliver AJ, Martelotto LG, Kirby L, Martin C, Patel RP, Slater A, Cullinane C, Papenfuss AT, Haynes NM, McArthur GA, Oliaro J, Sheppard KE. Lelliott EJ, et al. Among authors: mangiola s. Cancer Immunol Res. 2021 Feb;9(2):136-146. doi: 10.1158/2326-6066.CIR-20-0401. Epub 2020 Dec 10. Cancer Immunol Res. 2021. PMID: 33303574
The site of breast cancer metastases dictates their clonal composition and reversible transcriptomic profile.
Berthelet J, Wimmer VC, Whitfield HJ, Serrano A, Boudier T, Mangiola S, Merdas M, El-Saafin F, Baloyan D, Wilcox J, Wilcox S, Parslow AC, Papenfuss AT, Yeo B, Ernst M, Pal B, Anderson RL, Davis MJ, Rogers KL, Hollande F, Merino D. Berthelet J, et al. Among authors: mangiola s. Sci Adv. 2021 Jul 7;7(28):eabf4408. doi: 10.1126/sciadv.abf4408. Print 2021 Jul. Sci Adv. 2021. PMID: 34233875 Free PMC article.
Transcriptome sequencing and multi-plex imaging of prostate cancer microenvironment reveals a dominant role for monocytic cells in progression.
Mangiola S, McCoy P, Modrak M, Souza-Fonseca-Guimaraes F, Blashki D, Stuchbery R, Keam SP, Kerger M, Chow K, Nasa C, Le Page M, Lister N, Monard S, Peters J, Dundee P, Williams SG, Costello AJ, Neeson PJ, Pal B, Huntington ND, Corcoran NM, Papenfuss AT, Hovens CM. Mangiola S, et al. BMC Cancer. 2021 Jul 22;21(1):846. doi: 10.1186/s12885-021-08529-6. BMC Cancer. 2021. PMID: 34294073 Free PMC article.
46 results