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Therapeutic efficacy of an oral nucleoside analog of remdesivir against SARS-CoV-2 pathogenesis in mice.
Schäfer A, Martinez DR, Won JJ, Moreira FR, Brown AJ, Gully KL, Kalla R, Chun K, Du Pont V, Babusis D, Tang J, Murakami E, Subramanian R, Barrett KT, Bleier BJ, Bannister R, Feng JY, Bilello JP, Cihlar T, Mackman RL, Montgomery SA, Baric RS, Sheahan TP. Schäfer A, et al. bioRxiv [Preprint]. 2021 Sep 17:2021.09.13.460111. doi: 10.1101/2021.09.13.460111. bioRxiv. 2021. Update in: Sci Transl Med. 2022 May 4;14(643):eabm3410. doi: 10.1126/scitranslmed.abm3410 PMID: 34545367 Free PMC article. Updated. Preprint.
Release of severe acute respiratory syndrome coronavirus nuclear import block enhances host transcription in human lung cells.
Sims AC, Tilton SC, Menachery VD, Gralinski LE, Schäfer A, Matzke MM, Webb-Robertson BJ, Chang J, Luna ML, Long CE, Shukla AK, Bankhead AR 3rd, Burkett SE, Zornetzer G, Tseng CT, Metz TO, Pickles R, McWeeney S, Smith RD, Katze MG, Waters KM, Baric RS. Sims AC, et al. Among authors: schafer a. J Virol. 2013 Apr;87(7):3885-902. doi: 10.1128/JVI.02520-12. Epub 2013 Jan 30. J Virol. 2013. PMID: 23365422 Free PMC article.
Systems approaches to Coronavirus pathogenesis.
Schäfer A, Baric RS, Ferris MT. Schäfer A, et al. Curr Opin Virol. 2014 Jun;6:61-9. doi: 10.1016/j.coviro.2014.04.007. Epub 2014 May 17. Curr Opin Virol. 2014. PMID: 24842079 Free PMC article. Review.
Pathogenic influenza viruses and coronaviruses utilize similar and contrasting approaches to control interferon-stimulated gene responses.
Menachery VD, Eisfeld AJ, Schäfer A, Josset L, Sims AC, Proll S, Fan S, Li C, Neumann G, Tilton SC, Chang J, Gralinski LE, Long C, Green R, Williams CM, Weiss J, Matzke MM, Webb-Robertson BJ, Schepmoes AA, Shukla AK, Metz TO, Smith RD, Waters KM, Katze MG, Kawaoka Y, Baric RS. Menachery VD, et al. Among authors: schafer a. mBio. 2014 May 20;5(3):e01174-14. doi: 10.1128/mBio.01174-14. mBio. 2014. PMID: 24846384 Free PMC article.
The effect of inhibition of PP1 and TNFα signaling on pathogenesis of SARS coronavirus.
McDermott JE, Mitchell HD, Gralinski LE, Eisfeld AJ, Josset L, Bankhead A 3rd, Neumann G, Tilton SC, Schäfer A, Li C, Fan S, McWeeney S, Baric RS, Katze MG, Waters KM. McDermott JE, et al. Among authors: schafer a. BMC Syst Biol. 2016 Sep 23;10(1):93. doi: 10.1186/s12918-016-0336-6. BMC Syst Biol. 2016. PMID: 27663205 Free PMC article.
1,747 results