Sparreboom A - Search Results

1

Precision Dosing of Targeted Therapies Is Ready for Prime Time.

Groenland SL, Verheijen RB, Joerger M, Mathijssen RHJ, Sparreboom A, Beijnen JH, Beumer JH, Steeghs N, Huitema ADR. Groenland SL, et al. Among authors: sparreboom a. Clin Cancer Res. 2021 Dec 15;27(24):6644-6652. doi: 10.1158/1078-0432.CCR-20-4555. Epub 2021 Sep 21. Clin Cancer Res. 2021. PMID: 34548319 Free PMC article.

2

Isolation, purification, and biological activity of mono- and dihydroxylated paclitaxel metabolites from human feces.

Sparreboom A, Huizing MT, Boesen JJ, Nooijen WJ, van Tellingen O, Beijnen JH. Sparreboom A, et al. Cancer Chemother Pharmacol. 1995;36(4):299-304. doi: 10.1007/BF00689047. Cancer Chemother Pharmacol. 1995. PMID: 7628049

3

Determination of paclitaxel and metabolites in mouse plasma, tissues, urine and faeces by semi-automated reversed-phase high-performance liquid chromatography.

Sparreboom A, van Tellingen O, Nooijen WJ, Beijnen JH. Sparreboom A, et al. J Chromatogr B Biomed Appl. 1995 Feb 17;664(2):383-91. doi: 10.1016/0378-4347(94)00495-q. J Chromatogr B Biomed Appl. 1995. PMID: 7780591

4

Nonlinear pharmacokinetics of paclitaxel in mice results from the pharmaceutical vehicle Cremophor EL.

Sparreboom A, van Tellingen O, Nooijen WJ, Beijnen JH. Sparreboom A, et al. Cancer Res. 1996 May 1;56(9):2112-5. Cancer Res. 1996. PMID: 8616858

5

Tissue distribution, metabolism and excretion of paclitaxel in mice.

Sparreboom A, van Tellingen O, Nooijen WJ, Beijnen JH. Sparreboom A, et al. Anticancer Drugs. 1996 Jan;7(1):78-86. doi: 10.1097/00001813-199601000-00009. Anticancer Drugs. 1996. PMID: 8742102

6

Isolation, purification and biological activity of major docetaxel metabolites from human feces.

Sparreboom A, Van Tellingen O, Scherrenburg EJ, Boesen JJ, Huizing MT, Nooijen WJ, Versluis C, Beijnen JH. Sparreboom A, et al. Drug Metab Dispos. 1996 Jun;24(6):655-8. Drug Metab Dispos. 1996. PMID: 8781781

7

Quantification of paclitaxel metabolites in human plasma by high-performance liquid chromatography.

Huizing MT, Sparreboom A, Rosing H, van Tellingen O, Pinedo HM, Beijnen JH. Huizing MT, et al. Among authors: sparreboom a. J Chromatogr B Biomed Appl. 1995 Dec 15;674(2):261-8. doi: 10.1016/0378-4347(95)00308-8. J Chromatogr B Biomed Appl. 1995. PMID: 8788155

8

Determination of polyoxyethyleneglycerol triricinoleate 35 (Cremophor EL) in plasma by pre-column derivatization and reversed-phase high-performance liquid chromatography.

Sparreboom A, van Tellingen O, Huizing MT, Nooijen WJ, Beijnen JH. Sparreboom A, et al. J Chromatogr B Biomed Appl. 1996 Jun 7;681(2):355-62. doi: 10.1016/0378-4347(95)00544-7. J Chromatogr B Biomed Appl. 1996. PMID: 8811447

9

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine.

Sparreboom A, van Asperen J, Mayer U, Schinkel AH, Smit JW, Meijer DK, Borst P, Nooijen WJ, Beijnen JH, van Tellingen O. Sparreboom A, et al. Proc Natl Acad Sci U S A. 1997 Mar 4;94(5):2031-5. doi: 10.1073/pnas.94.5.2031. Proc Natl Acad Sci U S A. 1997. PMID: 9050899 Free PMC article.

10

Enhanced oral bioavailability of paclitaxel in mice treated with the P-glycoprotein blocker SDZ PSC 833.

van Asperen J, van Tellingen O, Sparreboom A, Schinkel AH, Borst P, Nooijen WJ, Beijnen JH. van Asperen J, et al. Among authors: sparreboom a. Br J Cancer. 1997;76(9):1181-3. doi: 10.1038/bjc.1997.530. Br J Cancer. 1997. PMID: 9365166 Free PMC article.

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