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Biliverdin reductase isozymes in metabolism.
O'Brien L, Hosick PA, John K, Stec DE, Hinds TD Jr. O'Brien L, et al. Among authors: stec de. Trends Endocrinol Metab. 2015 Apr;26(4):212-20. doi: 10.1016/j.tem.2015.02.001. Epub 2015 Feb 25. Trends Endocrinol Metab. 2015. PMID: 25726384 Free PMC article. Review.
Bilirubin Binding to PPARα Inhibits Lipid Accumulation.
Stec DE, John K, Trabbic CJ, Luniwal A, Hankins MW, Baum J, Hinds TD Jr. Stec DE, et al. PLoS One. 2016 Apr 12;11(4):e0153427. doi: 10.1371/journal.pone.0153427. eCollection 2016. PLoS One. 2016. PMID: 27071062 Free PMC article.
Biliverdin Reductase A Attenuates Hepatic Steatosis by Inhibition of Glycogen Synthase Kinase (GSK) 3β Phosphorylation of Serine 73 of Peroxisome Proliferator-activated Receptor (PPAR) α.
Hinds TD Jr, Burns KA, Hosick PA, McBeth L, Nestor-Kalinoski A, Drummond HA, AlAmodi AA, Hankins MW, Vanden Heuvel JP, Stec DE. Hinds TD Jr, et al. Among authors: stec de. J Biol Chem. 2016 Nov 25;291(48):25179-25191. doi: 10.1074/jbc.M116.731703. Epub 2016 Oct 10. J Biol Chem. 2016. PMID: 27738106 Free PMC article.
Mice with hyperbilirubinemia due to Gilbert's syndrome polymorphism are resistant to hepatic steatosis by decreased serine 73 phosphorylation of PPARα.
Hinds TD Jr, Hosick PA, Chen S, Tukey RH, Hankins MW, Nestor-Kalinoski A, Stec DE. Hinds TD Jr, et al. Among authors: stec de. Am J Physiol Endocrinol Metab. 2017 Apr 1;312(4):E244-E252. doi: 10.1152/ajpendo.00396.2016. Epub 2017 Jan 17. Am J Physiol Endocrinol Metab. 2017. PMID: 28096081 Free PMC article.
Bilirubin in the Liver-Gut Signaling Axis.
Hamoud AR, Weaver L, Stec DE, Hinds TD Jr. Hamoud AR, et al. Among authors: stec de. Trends Endocrinol Metab. 2018 Mar;29(3):140-150. doi: 10.1016/j.tem.2018.01.002. Epub 2018 Feb 3. Trends Endocrinol Metab. 2018. PMID: 29409713 Free PMC article. Review.
136 results