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Hypoxia and TLR9 activation drive CXCL4 production in systemic sclerosis plasmacytoid dendritic cells via mtROS and HIF-2α.
Ottria A, Zimmermann M, Paardekooper LM, Carvalheiro T, Vazirpanah N, Silva-Cardoso S, Affandi AJ, Chouri E, V D Kroef M, Tieland RG, Bekker CPJ, Wichers CGK, Rossato M, Mocholi-Gimeno E, Tekstra J, Ton E, van Laar JM, Cossu M, Beretta L, Garcia Perez S, Pandit A, Bonte-Mineur F, Reedquist KA, van den Bogaart G, Radstake TRDJ, Marut W. Ottria A, et al. Among authors: van den bogaart g, van laar jm. Rheumatology (Oxford). 2022 May 30;61(6):2682-2693. doi: 10.1093/rheumatology/keab532. Rheumatology (Oxford). 2022. PMID: 34559222
Microscale thermophoresis quantifies biomolecular interactions under previously challenging conditions.
Seidel SA, Dijkman PM, Lea WA, van den Bogaart G, Jerabek-Willemsen M, Lazic A, Joseph JS, Srinivasan P, Baaske P, Simeonov A, Katritch I, Melo FA, Ladbury JE, Schreiber G, Watts A, Braun D, Duhr S. Seidel SA, et al. Among authors: van den bogaart g. Methods. 2013 Mar;59(3):301-15. doi: 10.1016/j.ymeth.2012.12.005. Epub 2012 Dec 24. Methods. 2013. PMID: 23270813 Free PMC article. Review.
Lipid peroxidation causes endosomal antigen release for cross-presentation.
Dingjan I, Verboogen DR, Paardekooper LM, Revelo NH, Sittig SP, Visser LJ, Mollard GF, Henriet SS, Figdor CG, Ter Beest M, van den Bogaart G. Dingjan I, et al. Among authors: van den bogaart g. Sci Rep. 2016 Feb 24;6:22064. doi: 10.1038/srep22064. Sci Rep. 2016. PMID: 26907999 Free PMC article.
VAMP8-mediated NOX2 recruitment to endosomes is necessary for antigen release.
Dingjan I, Paardekooper LM, Verboogen DRJ, von Mollard GF, Ter Beest M, van den Bogaart G. Dingjan I, et al. Among authors: van den bogaart g. Eur J Cell Biol. 2017 Oct;96(7):705-714. doi: 10.1016/j.ejcb.2017.06.007. Epub 2017 Jun 23. Eur J Cell Biol. 2017. PMID: 28688576 Free PMC article.
Ethylene, an early marker of systemic inflammation in humans.
Paardekooper LM, van den Bogaart G, Kox M, Dingjan I, Neerincx AH, Bendix MB, Beest MT, Harren FJM, Risby T, Pickkers P, Marczin N, Cristescu SM. Paardekooper LM, et al. Among authors: van den bogaart g. Sci Rep. 2017 Jul 31;7(1):6889. doi: 10.1038/s41598-017-05930-9. Sci Rep. 2017. PMID: 28761087 Free PMC article.
Radical Stress Is More Cytotoxic in the Nucleus than in Other Organelles.
Paardekooper LM, van Vroonhoven E, Ter Beest M, van den Bogaart G. Paardekooper LM, et al. Among authors: van den bogaart g, van vroonhoven e. Int J Mol Sci. 2019 Aug 25;20(17):4147. doi: 10.3390/ijms20174147. Int J Mol Sci. 2019. PMID: 31450682 Free PMC article.
Interleukin-6 secretion is limited by self-signaling in endosomes.
Verboogen DRJ, Revelo NH, Ter Beest M, van den Bogaart G. Verboogen DRJ, et al. Among authors: van den bogaart g. J Mol Cell Biol. 2019 Feb 1;11(2):144-157. doi: 10.1093/jmcb/mjy038. J Mol Cell Biol. 2019. PMID: 30016456 Free PMC article.
107 results