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Page 1
Brief homogeneous TCR signals instruct common iNKT progenitors whose effector diversification is characterized by subsequent cytokine signaling.
Bortoluzzi S, Dashtsoodol N, Engleitner T, Drees C, Helmrath S, Mir J, Toska A, Flossdorf M, Öllinger R, Solovey M, Colomé-Tatché M, Kalfaoglu B, Ono M, Buch T, Ammon T, Rad R, Schmidt-Supprian M. Bortoluzzi S, et al. Among authors: flossdorf m. Immunity. 2021 Nov 9;54(11):2497-2513.e9. doi: 10.1016/j.immuni.2021.09.003. Epub 2021 Sep 24. Immunity. 2021. PMID: 34562377 Free article.
Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment.
Falcomatà C, Bärthel S, Widholz SA, Schneeweis C, Montero JJ, Toska A, Mir J, Kaltenbacher T, Heetmeyer J, Swietlik JJ, Cheng JY, Teodorescu B, Reichert O, Schmitt C, Grabichler K, Coluccio A, Boniolo F, Veltkamp C, Zukowska M, Vargas AA, Paik WH, Jesinghaus M, Steiger K, Maresch R, Öllinger R, Ammon T, Baranov O, Robles MS, Rechenberger J, Kuster B, Meissner F, Reichert M, Flossdorf M, Rad R, Schmidt-Supprian M, Schneider G, Saur D. Falcomatà C, et al. Among authors: flossdorf m. Nat Cancer. 2022 Mar;3(3):318-336. doi: 10.1038/s43018-021-00326-1. Epub 2022 Jan 31. Nat Cancer. 2022. PMID: 35122074 Free PMC article.
Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection.
Flommersfeld S, Böttcher JP, Ersching J, Flossdorf M, Meiser P, Pachmayr LO, Leube J, Hensel I, Jarosch S, Zhang Q, Chaudhry MZ, Andrae I, Schiemann M, Busch DH, Cicin-Sain L, Sun JC, Gasteiger G, Victora GD, Höfer T, Buchholz VR, Grassmann S. Flommersfeld S, et al. Among authors: flossdorf m. Immunity. 2021 Oct 12;54(10):2288-2304.e7. doi: 10.1016/j.immuni.2021.08.002. Epub 2021 Aug 25. Immunity. 2021. PMID: 34437840 Free PMC article.
Individual T helper cells have a quantitative cytokine memory.
Helmstetter C, Flossdorf M, Peine M, Kupz A, Zhu J, Hegazy AN, Duque-Correa MA, Zhang Q, Vainshtein Y, Radbruch A, Kaufmann SH, Paul WE, Höfer T, Löhning M. Helmstetter C, et al. Among authors: flossdorf m. Immunity. 2015 Jan 20;42(1):108-22. doi: 10.1016/j.immuni.2014.12.018. Epub 2014 Dec 25. Immunity. 2015. PMID: 25607461 Free PMC article.
Early emergence of T central memory precursors programs clonal dominance during chronic viral infection.
Grassmann S, Mihatsch L, Mir J, Kazeroonian A, Rahimi R, Flommersfeld S, Schober K, Hensel I, Leube J, Pachmayr LO, Kretschmer L, Zhang Q, Jolly A, Chaudhry MZ, Schiemann M, Cicin-Sain L, Höfer T, Busch DH, Flossdorf M, Buchholz VR. Grassmann S, et al. Among authors: flossdorf m. Nat Immunol. 2020 Dec;21(12):1563-1573. doi: 10.1038/s41590-020-00807-y. Epub 2020 Oct 26. Nat Immunol. 2020. PMID: 33106669
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