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Carnitine is a pharmacological allosteric chaperone of the human lysosomal α-glucosidase.
Iacono R, Minopoli N, Ferrara MC, Tarallo A, Damiano C, Porto C, Strollo S, Roig-Zamboni V, Peluso G, Sulzenbacher G, Cobucci-Ponzano B, Parenti G, Moracci M. Iacono R, et al. Among authors: sulzenbacher g. J Enzyme Inhib Med Chem. 2021 Dec;36(1):2068-2079. doi: 10.1080/14756366.2021.1975694. J Enzyme Inhib Med Chem. 2021. PMID: 34565280 Free PMC article.
Structure of Escherichia coli YhdH, a putative quinone oxidoreductase.
Sulzenbacher G, Roig-Zamboni V, Pagot F, Grisel S, Salomoni A, Valencia C, Campanacci V, Vincentelli R, Tegoni M, Eklund H, Cambillau C. Sulzenbacher G, et al. Acta Crystallogr D Biol Crystallogr. 2004 Oct;60(Pt 10):1855-62. doi: 10.1107/S0907444904020220. Epub 2004 Sep 23. Acta Crystallogr D Biol Crystallogr. 2004. PMID: 15388933
1,6-epi-Cyclophellitol Cyclosulfamidate Is a Bona Fide Lysosomal α-Glucosidase Stabilizer for the Treatment of Pompe Disease.
Kok K, Kuo CL, Katzy RE, Lelieveld LT, Wu L, Roig-Zamboni V, van der Marel GA, Codée JDC, Sulzenbacher G, Davies GJ, Overkleeft HS, Aerts JMFG, Artola M. Kok K, et al. Among authors: sulzenbacher g. J Am Chem Soc. 2022 Aug 17;144(32):14819-14827. doi: 10.1021/jacs.2c05666. Epub 2022 Aug 2. J Am Chem Soc. 2022. PMID: 35917590 Free PMC article.
48 results