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Page 1
Systems Biology of the Vasopressin V2 Receptor: New Tools for Discovery of Molecular Actions of a GPCR.
Chen L, Jung HJ, Datta A, Park E, Poll BG, Kikuchi H, Leo KT, Mehta Y, Lewis S, Khundmiri SJ, Khan S, Chou CL, Raghuram V, Yang CR, Knepper MA. Chen L, et al. Among authors: leo kt. Annu Rev Pharmacol Toxicol. 2022 Jan 6;62:595-616. doi: 10.1146/annurev-pharmtox-052120-011012. Epub 2021 Sep 27. Annu Rev Pharmacol Toxicol. 2022. PMID: 34579536 Free PMC article. Review.
"ADPKD-omics": determinants of cyclic AMP levels in renal epithelial cells.
Mehta YR, Lewis SA, Leo KT, Chen L, Park E, Raghuram V, Chou CL, Yang CR, Kikuchi H, Khundmiri S, Poll BG, Knepper MA. Mehta YR, et al. Among authors: leo kt. Kidney Int. 2022 Jan;101(1):47-62. doi: 10.1016/j.kint.2021.10.014. Epub 2021 Oct 29. Kidney Int. 2022. PMID: 34757121 Free PMC article. Review.
Machine learning-driven multifunctional peptide engineering for sustained ocular drug delivery.
Hsueh HT, Chou RT, Rai U, Liyanage W, Kim YC, Appell MB, Pejavar J, Leo KT, Davison C, Kolodziejski P, Mozzer A, Kwon H, Sista M, Anders NM, Hemingway A, Rompicharla SVK, Edwards M, Pitha I, Hanes J, Cummings MP, Ensign LM. Hsueh HT, et al. Among authors: leo kt. Nat Commun. 2023 May 2;14(1):2509. doi: 10.1038/s41467-023-38056-w. Nat Commun. 2023. PMID: 37130851 Free PMC article.
Engineered peptide-drug conjugate provides sustained protection of retinal ganglion cells with topical administration in rats.
Hsueh HT, Chou RT, Rai U, Kolodziejski P, Liyanage W, Pejavar J, Mozzer A, Davison C, Appell MB, Kim YC, Leo KT, Kwon H, Sista M, Anders NM, Hemingway A, Rompicharla SVK, Pitha I, Zack DJ, Hanes J, Cummings MP, Ensign LM. Hsueh HT, et al. Among authors: leo kt. J Control Release. 2023 Oct;362:371-380. doi: 10.1016/j.jconrel.2023.08.058. Epub 2023 Sep 4. J Control Release. 2023. PMID: 37657693 Free PMC article.
A hypotonic gel-forming eye drop provides enhanced intraocular delivery of a kinase inhibitor with melanin-binding properties for sustained protection of retinal ganglion cells.
Kim YC, Hsueh HT, Shin MD, Berlinicke CA, Han H, Anders NM, Hemingway A, Leo KT, Chou RT, Kwon H, Appell MB, Rai U, Kolodziejski P, Eberhart C, Pitha I, Zack DJ, Hanes J, Ensign LM. Kim YC, et al. Among authors: leo kt. Drug Deliv Transl Res. 2022 Apr;12(4):826-837. doi: 10.1007/s13346-021-00987-6. Epub 2021 Apr 26. Drug Deliv Transl Res. 2022. PMID: 33900546 Free PMC article.
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