Knebel A - Search Results

1

Structural basis for the specificity of PPM1H phosphatase for Rab GTPases.

Waschbüsch D, Berndsen K, Lis P, Knebel A, Lam YP, Alessi DR, Khan AR. Waschbüsch D, et al. Among authors: knebel a. EMBO Rep. 2021 Nov 4;22(11):e52675. doi: 10.15252/embr.202152675. Epub 2021 Sep 28. EMBO Rep. 2021. PMID: 34580980 Free PMC article.

2

The tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells.

Cartlidge RA, Knebel A, Peggie M, Alexandrov A, Phizicky EM, Cohen P. Cartlidge RA, et al. Among authors: knebel a. EMBO J. 2005 May 4;24(9):1696-705. doi: 10.1038/sj.emboj.7600648. Epub 2005 Apr 14. EMBO J. 2005. PMID: 15861136 Free PMC article.

3

LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activity.

Jaleel M, Nichols RJ, Deak M, Campbell DG, Gillardon F, Knebel A, Alessi DR. Jaleel M, et al. Among authors: knebel a. Biochem J. 2007 Jul 15;405(2):307-17. doi: 10.1042/BJ20070209. Biochem J. 2007. PMID: 17447891 Free PMC article.

4

PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65.

Kondapalli C, Kazlauskaite A, Zhang N, Woodroof HI, Campbell DG, Gourlay R, Burchell L, Walden H, Macartney TJ, Deak M, Knebel A, Alessi DR, Muqit MM. Kondapalli C, et al. Among authors: knebel a. Open Biol. 2012 May;2(5):120080. doi: 10.1098/rsob.120080. Open Biol. 2012. PMID: 22724072 Free PMC article.

5

The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction.

Ohta A, Schumacher FR, Mehellou Y, Johnson C, Knebel A, Macartney TJ, Wood NT, Alessi DR, Kurz T. Ohta A, et al. Among authors: knebel a. Biochem J. 2013 Apr 1;451(1):111-22. doi: 10.1042/BJ20121903. Biochem J. 2013. PMID: 23387299 Free PMC article.

6

Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65.

Kazlauskaite A, Kondapalli C, Gourlay R, Campbell DG, Ritorto MS, Hofmann K, Alessi DR, Knebel A, Trost M, Muqit MM. Kazlauskaite A, et al. Among authors: knebel a. Biochem J. 2014 May 15;460(1):127-39. doi: 10.1042/BJ20140334. Biochem J. 2014. PMID: 24660806 Free PMC article.

7

Screening of DUB activity and specificity by MALDI-TOF mass spectrometry.

Ritorto MS, Ewan R, Perez-Oliva AB, Knebel A, Buhrlage SJ, Wightman M, Kelly SM, Wood NT, Virdee S, Gray NS, Morrice NA, Alessi DR, Trost M. Ritorto MS, et al. Among authors: knebel a. Nat Commun. 2014 Aug 27;5:4763. doi: 10.1038/ncomms5763. Nat Commun. 2014. PMID: 25159004 Free PMC article.

8

Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation.

Kazlauskaite A, Martínez-Torres RJ, Wilkie S, Kumar A, Peltier J, Gonzalez A, Johnson C, Zhang J, Hope AG, Peggie M, Trost M, van Aalten DM, Alessi DR, Prescott AR, Knebel A, Walden H, Muqit MM. Kazlauskaite A, et al. Among authors: knebel a. EMBO Rep. 2015 Aug;16(8):939-54. doi: 10.15252/embr.201540352. Epub 2015 Jun 25. EMBO Rep. 2015. PMID: 26116755 Free PMC article.

9

A single MIU motif of MINDY-1 recognizes K48-linked polyubiquitin chains.

Kristariyanto YA, Abdul Rehman SA, Weidlich S, Knebel A, Kulathu Y. Kristariyanto YA, et al. Among authors: knebel a. EMBO Rep. 2017 Mar;18(3):392-402. doi: 10.15252/embr.201643205. Epub 2017 Jan 12. EMBO Rep. 2017. PMID: 28082312 Free PMC article.

10

Rab-GTPase binding effector protein 2 (RABEP2) is a primed substrate for Glycogen Synthase kinase-3 (GSK3).

Logie L, Van Aalten L, Knebel A, Force T, Hastie CJ, MacLauchlan H, Campbell DG, Gourlay R, Prescott A, Davidson J, Fuller W, Sutherland C. Logie L, et al. Among authors: knebel a. Sci Rep. 2017 Dec 15;7(1):17682. doi: 10.1038/s41598-017-17087-6. Sci Rep. 2017. PMID: 29247183 Free PMC article.

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