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Rational Combination of CRM1 Inhibitor Selinexor and Olaparib Shows Synergy in Ovarian Cancer Cell Lines and Mouse Models.
Handley KF, Rodriguez-Aguayo C, Ma S, Stur E, Joseph R, Bayraktar E, Dasari SK, Nguyen N, Powell RT, Sobieski M, Ivan C, Kim M, Umamaheswaran S, Glassman D, Wen Y, Amero P, Stephan C, Coleman RL, Landesman Y, Westin SN, Ram PT, Sood AK. Handley KF, et al. Among authors: joseph r. Mol Cancer Ther. 2021 Dec;20(12):2352-2361. doi: 10.1158/1535-7163.MCT-21-0370. Epub 2021 Sep 28. Mol Cancer Ther. 2021. PMID: 34583979 Free PMC article.
GSK3β regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer.
Vijay GV, Zhao N, Den Hollander P, Toneff MJ, Joseph R, Pietila M, Taube JH, Sarkar TR, Ramirez-Pena E, Werden SJ, Shariati M, Gao R, Sobieski M, Stephan CC, Sphyris N, Miura N, Davies P, Chang JT, Soundararajan R, Rosen JM, Mani SA. Vijay GV, et al. Among authors: joseph r. Breast Cancer Res. 2019 Mar 7;21(1):37. doi: 10.1186/s13058-019-1125-0. Breast Cancer Res. 2019. PMID: 30845991 Free PMC article.
CD8+ T cells inhibit metastasis and CXCL4 regulates its function.
Joseph R, Soundararajan R, Vasaikar S, Yang F, Allton KL, Tian L, den Hollander P, Isgandarova S, Haemmerle M, Mino B, Zhou T, Shin C, Martinez-Paniagua M, Sahin AA, Rodriguez-Canales J, Gelovani J, Chang JT, Acharya G, Sood AK, Wistuba II, Gibbons DL, Solis LM, Barton MC, Varadarajan N, Rosen JM, Zhang XH, Mani SA. Joseph R, et al. Br J Cancer. 2021 Jul;125(2):176-189. doi: 10.1038/s41416-021-01338-5. Epub 2021 Apr 1. Br J Cancer. 2021. PMID: 33795809 Free PMC article.
Combination of EphA2- and Wee1-Targeted Therapies in Endometrial Cancer.
Dasari SK, Joseph R, Umamaheswaran S, Mangala LS, Bayraktar E, Rodriguez-Aguayo C, Wu Y, Nguyen N, Powell RT, Sobieski M, Liu Y, Chowdhury MA, Amero P, Stephan C, Lopez-Berestein G, Westin SN, Sood AK. Dasari SK, et al. Among authors: joseph r. Int J Mol Sci. 2023 Feb 15;24(4):3915. doi: 10.3390/ijms24043915. Int J Mol Sci. 2023. PMID: 36835335 Free PMC article.
EphA2- and HDAC-Targeted Combination Therapy in Endometrial Cancer.
Joseph R, Dasari SK, Umamaheswaran S, Mangala LS, Bayraktar E, Rodriguez-Aguayo C, Wu Y, Nguyen N, Powell RT, Sobieski M, Liu Y, Kim MS, Corvigno S, Foster K, Hanjra P, Vu TC, Chowdhury MA, Amero P, Stephan C, Lopez-Berestein G, Westin SN, Sood AK. Joseph R, et al. Int J Mol Sci. 2024 Jan 20;25(2):1278. doi: 10.3390/ijms25021278. Int J Mol Sci. 2024. PMID: 38279277 Free PMC article.
Enrichment of Cancer Stem Cells in a Tumorsphere Assay.
Deshmukh AP, den Hollander P, Kuburich NA, Vasaikar S, Joseph R, Mani SA. Deshmukh AP, et al. Among authors: joseph r. Methods Mol Biol. 2022;2429:501-507. doi: 10.1007/978-1-0716-1979-7_34. Methods Mol Biol. 2022. PMID: 35507184
Inhibition of FOXC2 restores epithelial phenotype and drug sensitivity in prostate cancer cells with stem-cell properties.
Paranjape AN, Soundararajan R, Werden SJ, Joseph R, Taube JH, Liu H, Rodriguez-Canales J, Sphyris N, Wistuba I, Miura N, Dhillon J, Mahajan N, Mahajan K, Chang JT, Ittmann M, Maity SN, Logothetis C, Tang DG, Mani SA. Paranjape AN, et al. Among authors: joseph r. Oncogene. 2016 Nov 17;35(46):5963-5976. doi: 10.1038/onc.2015.498. Epub 2016 Jan 25. Oncogene. 2016. PMID: 26804168 Free PMC article.
1,623 results