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Muscle-secreted neurturin couples myofiber oxidative metabolism and slow motor neuron identity.
Correia JC, Kelahmetoglu Y, Jannig PR, Schweingruber C, Shvaikovskaya D, Zhengye L, Cervenka I, Khan N, Stec M, Oliveira M, Nijssen J, Martínez-Redondo V, Ducommun S, Azzolini M, Lanner JT, Kleiner S, Hedlund E, Ruas JL. Correia JC, et al. Among authors: hedlund e. Cell Metab. 2021 Nov 2;33(11):2215-2230.e8. doi: 10.1016/j.cmet.2021.09.003. Epub 2021 Sep 29. Cell Metab. 2021. PMID: 34592133 Free article.
Neurturin is a PGC-1α1-controlled myokine that promotes motor neuron recruitment and neuromuscular junction formation.
Mills R, Taylor-Weiner H, Correia JC, Agudelo LZ, Allodi I, Kolonelou C, Martinez-Redondo V, Ferreira DMS, Nichterwitz S, Comley LH, Lundin V, Hedlund E, Ruas JL, Teixeira AI. Mills R, et al. Among authors: hedlund e. Mol Metab. 2018 Jan;7:12-22. doi: 10.1016/j.molmet.2017.11.001. Epub 2017 Nov 7. Mol Metab. 2018. PMID: 29157948 Free PMC article.
Modeling Motor Neuron Resilience in ALS Using Stem Cells.
Allodi I, Nijssen J, Benitez JA, Schweingruber C, Fuchs A, Bonvicini G, Cao M, Kiehn O, Hedlund E. Allodi I, et al. Among authors: hedlund e. Stem Cell Reports. 2019 Jun 11;12(6):1329-1341. doi: 10.1016/j.stemcr.2019.04.009. Epub 2019 May 9. Stem Cell Reports. 2019. PMID: 31080111 Free PMC article.
145 results