Mariappan TT - Search Results

1

Endogenous Plasma Kynurenic Acid in Human: A Newly Discovered Biomarker for Drug-Drug Interactions Involving Organic Anion Transporter 1 and 3 Inhibition.

Tang J, Shen H, Zhao X, Holenarsipur VK, Mariappan TT, Zhang Y, Panfen E, Zheng J, Humphreys WG, Lai Y. Tang J, et al. Among authors: mariappan tt. Drug Metab Dispos. 2021 Dec;49(12):1063-1069. doi: 10.1124/dmd.121.000486. Epub 2021 Oct 1. Drug Metab Dispos. 2021. PMID: 34599018

2

Endogenous Biomarkers to Assess Drug-Drug Interactions by Drug Transporters and Enzymes.

Mariappan TT, Shen H, Marathe P. Mariappan TT, et al. Curr Drug Metab. 2017 Oct 16;18(8):757-768. doi: 10.2174/1389200218666170724110818. Curr Drug Metab. 2017. PMID: 28738769 Review.

3

Evidence for the Validity of Pyridoxic Acid (PDA) as a Plasma-Based Endogenous Probe for OAT1 and OAT3 Function in Healthy Subjects.

Shen H, Holenarsipur VK, Mariappan TT, Drexler DM, Cantone JL, Rajanna P, Singh Gautam S, Zhang Y, Gan J, Shipkova PA, Marathe P, Humphreys WG. Shen H, et al. Among authors: mariappan tt. J Pharmacol Exp Ther. 2019 Jan;368(1):136-145. doi: 10.1124/jpet.118.252643. Epub 2018 Oct 25. J Pharmacol Exp Ther. 2019. PMID: 30361237 Clinical Trial.

4

Detection of Weak Organic Anion-Transporting Polypeptide 1B Inhibition by Probenecid with Plasma-Based Coproporphyrin in Humans.

Zhang Y, Holenarsipur VK, Kandoussi H, Zeng J, Mariappan TT, Sinz M, Shen H. Zhang Y, et al. Among authors: mariappan tt. Drug Metab Dispos. 2020 Oct;48(10):841-848. doi: 10.1124/dmd.120.000076. Epub 2020 Jul 28. Drug Metab Dispos. 2020. PMID: 32723847

5

Coproporphyrin-I: A Fluorescent, Endogenous Optimal Probe Substrate for ABCC2 (MRP2) Suitable for Vesicle-Based MRP2 Inhibition Assay.

Gilibili RR, Chatterjee S, Bagul P, Mosure KW, Murali BV, Mariappan TT, Mandlekar S, Lai Y. Gilibili RR, et al. Among authors: mariappan tt. Drug Metab Dispos. 2017 Jun;45(6):604-611. doi: 10.1124/dmd.116.074740. Epub 2017 Mar 21. Drug Metab Dispos. 2017. PMID: 28325716

6

Effect of pretreatment regimens of 1-aminobenzotriazole on metabolism and gastric emptying of probe compounds in rat.

Padmanabhan S, Kaur H, Rao A, Saxena A, Gupta YK, Mariappan TT, Holenarsipur VK. Padmanabhan S, et al. Among authors: mariappan tt. Xenobiotica. 2019 Jun;49(6):646-654. doi: 10.1080/00498254.2018.1489166. Epub 2018 Sep 7. Xenobiotica. 2019. PMID: 29898636

7

Transporter Activity Changes in Nonalcoholic Steatohepatitis: Assessment with Plasma Coproporphyrin I and III.

Chatterjee S, Mukherjee S, Sankara Sivaprasad LVJ, Naik T, Gautam SS, Murali BV, Hadambar AA, Gunti GR, Kuchibhotla V, Deyati A, Basavanthappa S, Ramarao M, Mariappan TT, Zinker BA, Zhang Y, Sinz M, Shen H. Chatterjee S, et al. Among authors: mariappan tt. J Pharmacol Exp Ther. 2021 Jan;376(1):29-39. doi: 10.1124/jpet.120.000291. Epub 2020 Oct 30. J Pharmacol Exp Ther. 2021. PMID: 33127749

8

In Vitro Stimulation of Multidrug Resistance-Associated Protein 2 Function Is Not Reproduced In Vivo in Rats.

Gilibili RR, Kurawattimath V, Murali BV, Lai Y, Mariappan TT, Shen H, Chatterjee S. Gilibili RR, et al. Among authors: mariappan tt. Pharmaceutics. 2018 Aug 8;10(3):125. doi: 10.3390/pharmaceutics10030125. Pharmaceutics. 2018. PMID: 30096834 Free PMC article.

9

A modified serial blood sampling technique and utility of dried-blood spot technique in estimation of blood concentration: application in mouse pharmacokinetics.

Kurawattimath V, Pocha K, Mariappan TT, Trivedi RK, Mandlekar S. Kurawattimath V, et al. Among authors: mariappan tt. Eur J Drug Metab Pharmacokinet. 2012 Mar;37(1):23-30. doi: 10.1007/s13318-011-0066-5. Epub 2011 Sep 25. Eur J Drug Metab Pharmacokinet. 2012. PMID: 21948266

10

Insight into tissue unbound concentration: utility in drug discovery and development.

Mariappan TT, Mandlekar S, Marathe P. Mariappan TT, et al. Curr Drug Metab. 2013 Mar;14(3):324-40. doi: 10.2174/1389200211314030008. Curr Drug Metab. 2013. PMID: 23167621 Review.

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