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Page 1
Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation.
Cirnaru MD, Song S, Tshilenge KT, Corwin C, Mleczko J, Galicia Aguirre C, Benlhabib H, Bendl J, Apontes P, Fullard J, Creus-Muncunill J, Reyahi A, Nik AM, Carlsson P, Roussos P, Mooney SD, Ellerby LM, Ehrlich ME. Cirnaru MD, et al. Among authors: tshilenge kt. Elife. 2021 Oct 5;10:e65979. doi: 10.7554/eLife.65979. Elife. 2021. PMID: 34609283 Free PMC article.
Insulin-like growth factor 2 (IGF2) protects against Huntington's disease through the extracellular disposal of protein aggregates.
García-Huerta P, Troncoso-Escudero P, Wu D, Thiruvalluvan A, Cisternas-Olmedo M, Henríquez DR, Plate L, Chana-Cuevas P, Saquel C, Thielen P, Longo KA, Geddes BJ, Lederkremer GZ, Sharma N, Shenkman M, Naphade S, Sardi SP, Spichiger C, Richter HG, Court FA, Tshilenge KT, Ellerby LM, Wiseman RL, Gonzalez-Billault C, Bergink S, Vidal RL, Hetz C. García-Huerta P, et al. Among authors: tshilenge kt. Acta Neuropathol. 2020 Nov;140(5):737-764. doi: 10.1007/s00401-020-02183-1. Epub 2020 Jul 8. Acta Neuropathol. 2020. PMID: 32642868 Free PMC article.
FOXO3 targets are reprogrammed as Huntington's disease neural cells and striatal neurons face senescence with p16INK4a increase.
Voisin J, Farina F, Naphade S, Fontaine M, Tshilenge KT, Galicia Aguirre C, Lopez-Ramirez A, Dancourt J, Ginisty A, Sasidharan Nair S, Lakshika Madushani K, Zhang N, Lejeune FX, Verny M, Campisi J, Ellerby LM, Neri C. Voisin J, et al. Among authors: tshilenge kt. Aging Cell. 2020 Nov;19(11):e13226. doi: 10.1111/acel.13226. Epub 2020 Nov 6. Aging Cell. 2020. PMID: 33156570 Free PMC article.
Modulating FKBP5/FKBP51 and autophagy lowers HTT (huntingtin) levels.
Bailus BJ, Scheeler SM, Simons J, Sanchez MA, Tshilenge KT, Creus-Muncunill J, Naphade S, Lopez-Ramirez A, Zhang N, Lakshika Madushani K, Moroz S, Loureiro A, Schreiber KH, Hausch F, Kennedy BK, Ehrlich ME, Ellerby LM. Bailus BJ, et al. Among authors: tshilenge kt. Autophagy. 2021 Dec;17(12):4119-4140. doi: 10.1080/15548627.2021.1904489. Epub 2021 May 24. Autophagy. 2021. PMID: 34024231 Free PMC article.
PNA microprobe for label-free detection of expanded trinucleotide repeats.
Asefifeyzabadi N, Durocher G, Tshilenge KT, Alam T, Ellerby LM, Shamsi MH. Asefifeyzabadi N, et al. Among authors: tshilenge kt. RSC Adv. 2022 Mar 10;12(13):7757-7761. doi: 10.1039/d2ra00230b. eCollection 2022 Mar 8. RSC Adv. 2022. PMID: 35424746 Free PMC article.
Postnatal Conditional Deletion of Bcl11b in Striatal Projection Neurons Mimics the Transcriptional Signature of Huntington's Disease.
Song S, Creus Muncunill J, Galicia Aguirre C, Tshilenge KT, Hamilton BW, Gerencser AA, Benlhabib H, Cirnaru MD, Leid M, Mooney SD, Ellerby LM, Ehrlich ME. Song S, et al. Among authors: tshilenge kt. Biomedicines. 2022 Sep 23;10(10):2377. doi: 10.3390/biomedicines10102377. Biomedicines. 2022. PMID: 36289639 Free PMC article.
Proteomic Analysis of Huntington's Disease Medium Spiny Neurons Identifies Alterations in Lipid Droplets.
Tshilenge KT, Aguirre CG, Bons J, Gerencser AA, Basisty N, Song S, Rose J, Lopez-Ramirez A, Naphade S, Loureiro A, Battistoni E, Milani M, Wehrfritz C, Holtz A, Hetz C, Mooney SD, Schilling B, Ellerby LM. Tshilenge KT, et al. Mol Cell Proteomics. 2023 May;22(5):100534. doi: 10.1016/j.mcpro.2023.100534. Epub 2023 Mar 22. Mol Cell Proteomics. 2023. PMID: 36958627 Free PMC article.
15 results