Schmitt I - Search Results

1

Activators of alpha synuclein expression identified by reporter cell line-based high throughput drug screen.

Stahl F, Denner P, Piston D, Evert BO, de Boni L, Schmitt I, Breuer P, Wüllner U. Stahl F, et al. Among authors: schmitt i. Sci Rep. 2021 Oct 6;11(1):19857. doi: 10.1038/s41598-021-98841-9. Sci Rep. 2021. PMID: 34615900 Free PMC article.

2

Inflammatory genes are upregulated in expanded ataxin-3-expressing cell lines and spinocerebellar ataxia type 3 brains.

Evert BO, Vogt IR, Kindermann C, Ozimek L, de Vos RA, Brunt ER, Schmitt I, Klockgether T, Wüllner U. Evert BO, et al. Among authors: schmitt i. J Neurosci. 2001 Aug 1;21(15):5389-96. doi: 10.1523/JNEUROSCI.21-15-05389.2001. J Neurosci. 2001. PMID: 11466410 Free PMC article.

3

Structural modeling of ataxin-3 reveals distant homology to adaptins.

Albrecht M, Hoffmann D, Evert BO, Schmitt I, Wüllner U, Lengauer T. Albrecht M, et al. Among authors: schmitt i. Proteins. 2003 Feb 1;50(2):355-70. doi: 10.1002/prot.10280. Proteins. 2003. PMID: 12486728

4

The human MJD gene: genomic structure and functional characterization of the promoter region.

Schmitt I, Evert BO, Khazneh H, Klockgether T, Wuellner U. Schmitt I, et al. Gene. 2003 Sep 18;314:81-8. doi: 10.1016/s0378-1119(03)00706-6. Gene. 2003. PMID: 14527720

5

Rapamycin alleviates toxicity of different aggregate-prone proteins.

Berger Z, Ravikumar B, Menzies FM, Oroz LG, Underwood BR, Pangalos MN, Schmitt I, Wullner U, Evert BO, O'Kane CJ, Rubinsztein DC. Berger Z, et al. Among authors: schmitt i. Hum Mol Genet. 2006 Feb 1;15(3):433-42. doi: 10.1093/hmg/ddi458. Epub 2005 Dec 20. Hum Mol Genet. 2006. PMID: 16368705

6

Inactivation of the mouse Atxn3 (ataxin-3) gene increases protein ubiquitination.

Schmitt I, Linden M, Khazneh H, Evert BO, Breuer P, Klockgether T, Wuellner U. Schmitt I, et al. Biochem Biophys Res Commun. 2007 Oct 26;362(3):734-9. doi: 10.1016/j.bbrc.2007.08.062. Epub 2007 Aug 23. Biochem Biophys Res Commun. 2007. PMID: 17764659

7

CK2-dependent phosphorylation determines cellular localization and stability of ataxin-3.

Mueller T, Breuer P, Schmitt I, Walter J, Evert BO, Wüllner U. Mueller T, et al. Among authors: schmitt i. Hum Mol Genet. 2009 Sep 1;18(17):3334-43. doi: 10.1093/hmg/ddp274. Epub 2009 Jun 19. Hum Mol Genet. 2009. PMID: 19542537

8

Methylation regulates alpha-synuclein expression and is decreased in Parkinson's disease patients' brains.

Jowaed A, Schmitt I, Kaut O, Wüllner U. Jowaed A, et al. Among authors: schmitt i. J Neurosci. 2010 May 5;30(18):6355-9. doi: 10.1523/JNEUROSCI.6119-09.2010. J Neurosci. 2010. PMID: 20445061 Free PMC article.

9

Genome-scale methylation analysis of Parkinson's disease patients' brains reveals DNA hypomethylation and increased mRNA expression of cytochrome P450 2E1.

Kaut O, Schmitt I, Wüllner U. Kaut O, et al. Among authors: schmitt i. Neurogenetics. 2012 Feb;13(1):87-91. doi: 10.1007/s10048-011-0308-3. Epub 2012 Jan 12. Neurogenetics. 2012. PMID: 22238121

10

Variants in the 3'UTR of SNCA do not affect miRNA-433 binding and alpha-synuclein expression.

Schmitt I, Wüllner U, van Rooyen JP, Khazneh H, Becker J, Volk A, Kubisch C, Becker T, Kostic VS, Klein C, Ramirez A. Schmitt I, et al. Eur J Hum Genet. 2012 Dec;20(12):1265-9. doi: 10.1038/ejhg.2012.84. Epub 2012 May 23. Eur J Hum Genet. 2012. PMID: 22617348 Free PMC article.

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